Research

Research is integrated into practice at Mayo Clinic, and Mayo breast surgeons are involved in many research studies and clinical trials to discover new and improved methods of treatment.

Recent surgical research areas include:

Breast cancer

  • Ductal carcinoma in situ (DCIS) vaccine trial.
  • Cancer risks for changes, also called mutations, in breast cancer predisposition genes.
  • Robotic nipple-sparing mastectomy for patients at increased risk of breast cancer.
  • Robotic nipple-sparing mastectomy for patients with breast cancer.
  • Breast cancer cryotherapy.
  • Lymphatic mapping of the arm at the time of axillary lymph node surgery aimed at decreasing the risk of lymphedema.
  • Omission of axillary lymph node dissection in patients with positive sentinel nodes after neoadjuvant chemotherapy.
  • Lymph node dissection with immediate lymphatic reconstruction.
  • Nipple nerve grafting for selected patients undergoing nipple-sparing mastectomy, aiming to improve sensation after the procedure.
  • Use of an intraoperative device to assess surgical margins in real time during anesthesia.
  • Preoperative endocrine therapy prior to surgery.
  • Novel therapeutic agents in patients treated with neoadjuvant chemotherapy

Research labs

Explore research labs.

Related research centers and programs

Publications

See a list of publications about breast-related surgical topics by Mayo Clinic doctors on PubMed, a service of the National Library of Medicine.

Mayo Clinic has been recognized as a top cancer hospital by U.S. News & World Report since it began publishing rankings in 1990. Most recently, Mayo Clinic in Rochester, Minnesota, Mayo Clinic in Jacksonville, Florida, and Mayo Clinic in Phoenix/Scottsdale, Arizona, have been recognized among the top Cancer hospitals in the nation for 2024-2025 by U.S. News & World Report.