Michel Toledano, M.D.
Neurologist
Banks SA, Brinjikji W, Giannini C, Syc-Mazurek SB, Xeros HK,
Toledano M
, Mustafa R, Carabenciov ID, Tobin WO. Intra-arterial Melphalan as Targeted Therapy for Tumefactive Multiple Sclerosis Lesions. Neurology. 2024 Sep 10; 103 (5):e209739 Epub 2024 Aug 06
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Nathoo N, Neyal N, Atkinson EJ, Weinshenker BG, Tillema JM, Keegan BM, Pittock SJ, Tobin WO, Flanagan EP, Gavrilova R,
Toledano M
, Young N, Truitt K, Okuda DT, Zeydan B, Kantarci OH. Multiple sclerosis in Somali Americans: Nature or nurture? Mult Scler Relat Disord. 2024 Aug 28; 90:105842 [Epub ahead of print]
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Mangioris G, Pittock SJ, Yang B, Fryer JP, Harmsen WS, Dubey D, Flanagan EP, Lopez-Chiriboga SA, McKeon A, Mills JR, Vodopivec I, Tobin WO,
Toledano M
, Aksamit AJ, Zekeridou A. Cerebrospinal Fluid Cytokine and Chemokine Profiles in Central Nervous System Sarcoidosis: Diagnostic and Immunopathologic Insights. Ann Neurol. 2024 Jul 19 Epub 2024 July 19
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Redenbaugh V, Fryer JP, Cacciaguerra L, Chen JJ, Greenwood TM, Gilligan M, Thakolwiboon S, Majed M, Chia NH, McKeon A, Mills JR, Lopez Chiriboga AS, Tillema JM, Yang B, Abdulrahman Y, Guo K, Vorasoot N, Valencia Sanchez C, Tajfirouz DA,
Toledano M
, Zekeridou A, Dubey D, Gombolay GY, Caparo-Zamalloa C, Kister I, Pittock SJ, Flanagan EP. Diagnostic Utility of MOG Antibody Testing in Cerebrospinal Fluid. Ann Neurol. 2024 Jul; 96 (1):34-45 Epub 2024 Apr 09
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Nathoo N, Chodnicki KD, Van Gompel JJ, Krecke KN, Nguyen AT,
Toledano M
, Kantarci OH. Atypical Bilateral Idiopathic Inflammatory Cavernous Sinus Syndrome Responsive to Cyclophosphamide. Can J Neurol Sci. 2024 Mar 6; 1-3 Epub 2024 Mar 06
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Mendoza MA, Hass RM, Vaillant J, Johnson DR, Theel ES,
Toledano M
, Abu Saleh O. Powassan Virus Encephalitis: A Tertiary Center Experience. Clin Infect Dis. 2024 Jan 25; 78 (1):80-89
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Li X, Krecke KN, Weinshenker BG, Clarke MJ, Zekeridou A,
Toledano M
, Flanagan EP. Hemicord White Matter Enhancement and the Croissant Sign in Cervical Spondylotic Myelopathy. Neurology. 2023 Nov 21; 101 (21):968-969 Epub 2023 Aug 30
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Griffin KJ,
Toledano M
, Flanagan EP, Mustafa R. "Trident Sign" in Primary CNS B-Cell Spinal Cord Lymphoma. Neurology. 2023 Nov 7; 101 (19):857-858 Epub 2023 Aug 30
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Skolka MP, Neth BJ, Brown A, Steel SJ, Hacker K, Arnold C,
Toledano M
, Mustafa R. Improving Neurology Inpatient Fall Rate: Effect of a Collaborative Interdisciplinary Quality Improvement Initiative. Mayo Clin Proc Innov Qual Outcomes. 2023 Aug; 7(4):267-275. Epub 2023 Jun 25.
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McEntire CRS, Fletcher A,
Toledano M
, Epstein S, White E, Tan CS, Mao-Draayer Y, Banks SA, Aksamit AJ, Gelfand JM, Thakur KT, Anand P, Cortese I, Bhattacharyya S. Characteristics of Progressive Multifocal Leukoencephalopathy Associated With Sarcoidosis Without Therapeutic Immune Suppression. JAMA Neurol. 2023 Jun 1; 80 (6):624-633
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Ward RC, Klarich KW, Benarroch EE,
Toledano MM
, DeSimone CV. Lateral medullary infarction presenting as high-grade heart block. Pacing Clin Electrophysiol. 2023 Jun; 46 (6):498-500 Epub 2023 Mar 05
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Toledano M
. Neurologic Manifestations of Rheumatologic Disease. Continuum (Minneap Minn). 2023 Jun 1; 29 (3):734-762
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Rizzo SA, Flanagan EP, Trejo-Lopez JA,
Toledano M
, Chia NH. Clinical Reasoning: New-Onset Diplopia and Headache in a Patient With Metastatic Breast Cancer. Neurology. 2023 May 9; 100 (19):927-931 Epub 2023 Feb 20
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Skolka M, Pinto MV, Powell TE, Eggers S, Dahl H,
Toledano M
. Transient downbeat nystagmus. Pract Neurol. 2023 Feb; 23(1):93-94. Epub 2022 Aug 11.
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Fautsch KJ, Block DR, Graff-Radford J, Wang F, Craver EC, Hodge DO, Cutsforth-Gregory JK, Kilgore KP, Petersen RC, Knopman DS, Flanagan E,
Toledano M
, Mielke MM, Bhatti MT, Chen JJ. Population-Based Evaluation of Total Protein in Cerebrospinal Fluid. Mayo Clin Proc. 2023 Feb; 98 (2):239-251
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Saw JL, Hale J, Madhavan A, Ringler MD,
Toledano M
, Naddaf E. Ischiofemoral impingement syndrome provoked by labor: An unusual case of complete sciatic mononeuropathy. Neuroradiol J. 2023 Feb; 36 (1):116-118 Epub 2022 June 18
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Flanagan EP, Geschwind MD, Lopez-Chiriboga AS, Blackburn KM, Turaga S, Binks S, Zitser J, Gelfand JM, Day GS, Dunham SR, Rodenbeck SJ, Clardy SL, Solomon AJ, Pittock SJ, McKeon A, Dubey D, Zekeridou A,
Toledano M
, Turner LE, Vernino S, Irani SR. Autoimmune Encephalitis Misdiagnosis in Adults. JAMA Neurol. 2023 Jan 1; 80(1):30-39. Epub 1900 Jan 01.
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Flanagan EP, Geschwind MD, Lopez-Chiriboga AS, Blackburn KM, Turaga S, Binks S, Zitser J, Gelfand JM, Day GS, Dunham SR, Rodenbeck SJ, Clardy SL, Solomon AJ, Pittock SJ, McKeon A, Dubey D, Zekeridou A,
Toledano M
, Turner LE, Vernino S, Irani SR. Autoimmune Encephalitis Misdiagnosis in Adults. JAMA Neurol. 2023 Jan 1; 80 (1):30-39
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Chang BK, Day GS, Graff-Radford J, McKeon A, Flanagan EP, Algeciras-Schimnich A, Mielke MM, Nguyen A, Jones DT,
Toledano M
, Kremers WK, Knopman DS, Petersen RC, Li W. Alzheimer's disease cerebrospinal fluid biomarkers differentiate patients with Creutzfeldt-Jakob disease and autoimmune encephalitis. Eur J Neurol. 2022 Oct; 29 (10):2905-2912 Epub 2022 July 05
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Rodriguez A, Klein CJ, Sechi E, Alden E, Basso MR, Pudumjee S, Pittock SJ, McKeon A, Britton JW, Lopez-Chiriboga AS, Zekeridou A, Zalewski NL, Boeve BF, Day GS, Gadoth A, Burkholder D,
Toledano M
, Dubey D, Flanagan EP. LGI1 antibody encephalitis: acute treatment comparisons and outcome. J Neurol Neurosurg Psychiatry. 2022 Mar; 93 (3):309-315 Epub 2021 Nov 25
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Valencia Sanchez C, Theel E, Binnicker M,
Toledano M
, McKeon A. Autoimmune Encephalitis After SARS-CoV-2 Infection: Case Frequency, Findings, and Outcomes. Neurology. 2021 Dec 7; 97 (23):e2262-e2268 Epub 2021 Oct 11
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Mustafa R, Passe TJ, Lopez-Chiriboga AS, Weinshenker BG, Krecke KN, Zalewski NL, Diehn FE, Sechi E, Mandrekar J, Kaufmann TJ, Morris PP, Pittock SJ,
Toledano M
, Lanzino G, Aksamit AJ, Kumar N, Lucchinetti CF, Flanagan EP. Utility of MRI Enhancement Pattern in Myelopathies With Longitudinally Extensive T2 Lesions. Neurol Clin Pract. 2021 Oct; 11 (5):e601-e611
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Zhao-Fleming HH, Valencia Sanchez C, Sechi E, Inbarasu J, Wijdicks EF, Pittock SJ, Chen JJ, Wingerchuk DM, Weinshenker BG, Lopez-Chiriboga S, Dubey D, Tillema JM,
Toledano M
, Yadav H, Flanagan EP. CNS Demyelinating Attacks Requiring Ventilatory Support With Myelin Oligodendrocyte Glycoprotein or Aquaporin-4 Antibodies. Neurology. 2021 Sep 28; 97 (13):e1351-e1358 Epub 2021 Aug 13
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Sheikh MA,
Toledano M
, Ahmed S, Gul Z, Hashmi SK. Noninfectious neurologic complications of hematopoietic cell transplantation: A systematic review. Hematol Oncol Stem Cell Ther. 2021 Jun; 14 (2):87-94 Epub 2020 May 21
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Smith KM, Britton JW, Hocker SE,
Toledano M
. Hyperammonemia in Patients With Status Epilepticus Treated With or Without Valproic Acid. Neurologist. 2021 May 5; 26 (3):80-82 Epub 2021 May 05
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McKeon A, Shelly S, Zivelonghi C, Basal E, Dubey D, Flanagan E, Madhavan AA, Mariotto S,
Toledano M
, Tracy JA, Zekeridou A, Pittock SJ. Neuronal intermediate filament IgGs in CSF: Autoimmune Axonopathy Biomarkers. Ann Clin Transl Neurol. 2021 Feb; 8 (2):425-439 Epub 2020 Dec 28
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Toledano M
. Infectious Myelopathies. Continuum (Minneap Minn). 2021 Feb 01; 27(1):93-120.
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Cano Cevallos EJ, Corsini Campioli C, Pritt BS,
Toledano M
, Meyer FB, Kasten MJ, Wright AJ. Nocardia pituitary abscess in an immunocompetent host. IDCases. 2021; 26:e01352 Epub 2021 Nov 27
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Sytsma TT, Theel ES, Temesgan Z,
Toledano M
. Assessing Utilization of the Cerebrospinal Fluid Venereal Disease Research Laboratory Test for Diagnosis of Neurosyphilis: a Cohort Study. J Gen Intern Med. 2021 Jan; 36 (1):77-83 Epub 2020 Aug 31
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Rodino KG,
Toledano M
, Norgan AP, Pritt BS, Binnicker MJ, Yao JD, Aksamit AJ, Patel R. Retrospective Review of Clinical Utility of Shotgun Metagenomic Sequencing Testing of Cerebrospinal Fluid from a U.S. Tertiary Care Medical Center. J Clin Microbiol. 2020 Nov 18; 58 (12)
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Divani AA, Andalib S, Biller J, Di Napoli M, Moghimi N, Rubinos CA, O'Hana Nobleza C, Sylaja PN,
Toledano M
, Lattanzi S, McCullough LD, Cruz-Flores S, Torbey M, Azarpazhooh MR. Correction to: Central Nervous System Manifestations Associated with COVID-19. Curr Neurol Neurosci Rep. 2020 Nov 12; 20 (12):66
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Toledano M
. Toxin-Induced Neuropathies. Neurol Clin. 2020 Nov; 38 (4):749-763 Epub 2020 Sept 12
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Divani AA, Andalib S, Biller J, Di Napoli M, Moghimi N, Rubinos CA, Nobleza CO, Sylaja PN,
Toledano M
, Lattanzi S, McCullough LD, Cruz-Flores S, Torbey M, Azarpazhooh MR. Central Nervous System Manifestations Associated with COVID-19. Curr Neurol Neurosci Rep. 2020 Oct 30; 20 (12):60
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Naddaf E, Laughlin RS, Klein CJ,
Toledano M
, Theel ES, Binnicker MJ, Nagappan V, Abdulrazzak M, Phelan DM. Guillain-Barre Syndrome in a Patient With Evidence of Recent SARS-CoV-2 Infection. Mayo Clin Proc 2020 Aug; 95 (8):1799-1801 Epub 2020 June 10
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Cox BC, Mauermann ML, Theel ES,
Toledano M
. Clinical Reasoning: Multifocal neuropathies in a patient with Waldenstrom macroglobulinemia and prior borreliosis. Neurology. 2020 Jul 7; 95 (1):44-48 Epub 2020 June 11
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Paul P, McKeon A, Pittock SJ, Klein CJ, Shah S,
Toledano M
, Mills JR, Dubey D. GFAP IgG associated inflammatory polyneuropathy. J Neuroimmunol. 2020 Jun 15; 343:577233 Epub 2020 Apr 01
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Toledano M
, Davies NWS. Infectious encephalitis: mimics and chameleons. Pract Neurol. 2019 Jun; 19 (3):225-237 Epub 2019 Mar 16
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Toledano M
, Weinshenker BG, Kaufmann TJ, Parisi JE, Paz Soldan MM. Demographics and clinical characteristics of episodic hypothermia in multiple sclerosis. Mult Scler. 2019 Apr; 25 (5):709-714 Epub 2018 Mar 23
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Parks NE, Pittock SJ, Mandrekar J, Kantarci OH, Lucchinetti CF, Weinshenker BG, Keegan BM, Tobin WO, Tillema JM,
Toledano M
, Flanagan EP. Population-based study of "no evident disease activity" in MS. Neurol Neuroimmunol Neuroinflamm. 2018 Nov; 5 (6):e495 Epub 2018 Aug 16
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Hawkes MA,
Toledano M
, Kaufmann TJ, Rabinstein AA. West Nile Neuroinvasive Disease Presenting as Elsberg Syndrome. Neurologist. 2018 Sep; 23 (5):152-154
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Dubey D,
Toledano M
, McKeon A. Clinical presentation of autoimmune and viral encephalitides. Curr Opin Crit Care. 2018 Apr; 24 (2):80-90
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Dubey D, Pittock SJ, Kelly CR, McKeon A, Lopez-Chiriboga AS, Lennon VA, Gadoth A, Smith CY, Bryant SC, Klein CJ, Aksamit AJ,
Toledano M
, Boeve BF, Tillema JM, Flanagan EP. Autoimmune encephalitis epidemiology and a comparison to infectious encephalitis. Ann Neurol. 2018 Jan; 83 (1):166-177
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Savoldi F, Kaufmann TJ, Flanagan EP,
Toledano M
, Weinshenker BG. Elsberg syndrome: A rarely recognized cause of cauda equina syndrome and lower thoracic myelitis. Neurol Neuroimmunol Neuroinflamm. 2017 Jul; 4 (4):e355 Epub 2017 May 11
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Toledano M
, Fugate JE. Posterior reversible encephalopathy in the intensive care unit. Handb Clin Neurol. 2017; 141:467-483.
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Solomon AJ, Bourdette DN, Cross AH, Applebee A, Skidd PM, Howard DB, Spain RI, Cameron MH, Kim E, Mass MK, Yadav V, Whitham RH, Longbrake EE, Naismith RT, Wu GF, Parks BJ, Wingerchuk DM, Rabin BL,
Toledano M
, Tobin WO, Kantarci OH, Carter JL, Keegan BM, Weinshenker BG. The contemporary spectrum of multiple sclerosis misdiagnosis: A multicenter study. Neurology. 2016 Sep 27; 87 (13):1393-9 Epub 2016 Aug 31
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Toledano M
, Davies NW. Enteroviral Postencephalitic Parkinsonism With Evidence of Impaired Presynaptic Dopaminergic Function. JAMA Neurol. 2016 Aug 1; 73 (8):1023-5
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Toledano M
, Weinshenker BG, Solomon AJ. A Clinical Approach to the Differential Diagnosis of Multiple Sclerosis. Curr Neurol Neurosci Rep. 2015 Aug; 15 (8):57
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Toledano M
, Pittock SJ. Autoimmune Epilepsy. Semin Neurol. 2015 Jun; 35: (3)245-58.
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Toledano M
, Britton JW, McKeon A, Shin C, Lennon VA, Quek AM, So E, Worrell GA, Cascino GD, Klein CJ, Lagerlund TD, Wirrell EC, Nickels KC, Pittock SJ. Utility of an immunotherapy trial in evaluating patients with presumed autoimmune epilepsy. Neurology. 2014 May 6; 82 (18):1578-86 Epub 2014 Apr 04
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Toledano M
, Siddiqui MA, Thompson CA, Garza I, Pittock SJ. Teaching NeuroImages: diagnostic utility of FDG-PET in neurolymphomatosis. Neurology. 2013 Jul 2; 81 (1):e3
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Toledano M
, Bartleson JD. Cervical spondylotic myelopathy. Neurol Clin. 2013 Feb; 31 (1):287-305
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Toledano M
, Bhagra A. Pericardial calcification in constrictive pericarditis. Int J Emerg Med. 2012 Oct 13; 5 (1):37
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Kenney DL,
Toledano M
, Moseley BD. Hypothermia and corpus callosum agenesis in Shapiro syndrome: too cold, even for a Viking. Neurology. 2012 Aug 28; 79(9):e78.
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Huang JF,
Toledano M
, Katz BS, Lanzino G, Moseley BD. Teaching neuroImages: Seeing double: intercavernous sinus dural arteriovenous fistula causing bilateral abducens palsy. Neurology. 2012 Apr 10; 78: (15)e95-6.
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Lewis, Mizrahi M,
Toledano M
, Defelice N, Wright JL, Churg A, Shapiro L, Dinarello CA. alpha1-Antitrypsin monotherapy induces immune tolerance during islet allograft transplantation in mice. Proc Natl Acad Sci U S A.2008;
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