Lois E. Krahn, M.D.

  1. Psychiatrist
  2. Neurologist
  3. Interim Chief Executive Officer, Arizona
  1. Petrov ME, Epstein DR, Krahn L, Todd M, Park JG, St Louis EK, Morgenthaler TI, Hoffmann CM, Hasanaj K, Hollingshead K, Yu TY, Buman MP. SleepWell24, a Smartphone Application to Promote Adherence to Positive Airway Pressure Therapy: Feasibility and Acceptability in a Randomized Controlled Trial. Behav Sleep Med. 2024 Jul-Aug; 22 (4):420-432 Epub 2023 Nov 30
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  2. Thorpy MJ, Krahn L, Ruoff C, Foldvary-Schaefer N. Clinical considerations in the treatment of idiopathic hypersomnia. Sleep Med. 2024 Jul; 119:488-498 Epub 2024 May 07
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  3. Morse AM, Krahn L, Flygare J, Kushida C, Thorpy MJ, Athavale A, Gudeman J. Clinician Preferences for Oxybate Treatment for Narcolepsy: Survey and Discrete Choice Experiment. Adv Ther. 2023 Jul; 40 (7):3199-3216 Epub 2023 May 27
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  4. Ruoff CM, Tashman YS, Cheema KPK, Miller BW, Houser RF, Lizak MJ, Haley CC, Petersen AM, Goswami U, Lyng PJ, Krahn LE, Srivathsan K. Interaction of positive airway pressure mask magnets with cardiac implantable electronic devices. J Clin Sleep Med. 2023 May 1; 19 (5):941-946
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  5. Devarajan A, Paliwal A, Ruoff C, Lyng PJ, Lizak M, Krahn LE. Interaction between alcohol consumption and use of peripheral arterial tone home sleep apnea tests for sleep apnea evaluation. Sleep Med. 2023 Feb; 102:142-146 Epub 2022 Dec 30
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  6. Krahn LE, Zee PC, Thorpy MJ. Current Understanding of Narcolepsy 1 and its Comorbidities: What Clinicians Need to Know. Adv Ther. 2022 Jan; 39 (1):221-243 Epub 2021 Dec 11
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  7. Krahn LE, Arand DL, Avidan AY, Davila DG, DeBassio WA, Ruoff CM, Harrod CG. Recommended protocols for the Multiple Sleep Latency Test and Maintenance of Wakefulness Test in adults: guidance from the American Academy of Sleep Medicine. J Clin Sleep Med. 2021 Dec 1; 17 (12):2489-2498
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  8. Davis CW, Kallweit U, Schwartz JC, Krahn LE, Vaughn B, Thorpy MJ. Efficacy of pitolisant in patients with high burden of narcolepsy symptoms: pooled analysis of short-term, placebo-controlled studies. Sleep Med. 2021 May; 81:210-217 Epub 2021 Feb 24
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  9. Petrov ME, Hasanaj K, Hoffmann CM, Epstein DR, Krahn L, Park JG, Hollingshead K, Yu TY, Todd M, St Louis EK, Morgenthaler TI, Buman MP. Rationale, design, and development of SleepWell24: A smartphone application to promote adherence to positive airway pressure therapy among patients with obstructive sleep apnea. Contemp Clin Trials. 2020 Feb; 89:105908 Epub 2019 Dec 14
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  10. Nokes BT, Raza HA, Cartin-Ceba R, Lyng PJ, Krahn LE, Wesselius L, Jokerst CE, Umar SB, Griffing WL, Neville MR, Malhotra A, Parish JM. Individuals With Scleroderma May Have Increased Risk of Sleep-Disordered Breathing. J Clin Sleep Med. 2019 Nov 15; 15 (11):1665-1669
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  11. Krahn LE, Petersen A, Miller BW, Lizak M, Lyng P. Abnormal Pulse Oximetry Signal. J Clin Sleep Med. 2018 Jul 15; 14 (7):1255-1256 Epub 2018 July 15
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  12. Krahn LE. How Can We Encourage Medical Student Interest in Psychiatric Careers? Am J Psychiatry 2017 Sep 1; 174 (9):823-824
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  13. Patel SI, Miller BW, Kosiorek HE, Parish JM, Lyng PJ, Krahn LE. The Effect of Dogs on Human Sleep in the Home Sleep Environment. Mayo Clin Proc. 2017 Sep; 92 (9):1368-1372
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  14. Krahn LE, Tovar MD, Miller B. Are Pets in the Bedroom a Problem? Mayo Clin Proc. 2015 Dec; 90: (12)1663-5.
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  15. Bright RP, Krahn L. Value-added education: enhancing learning on the psychiatry inpatient consultation service. Acad Psychiatry. 2015 Apr; 39(2):212-4. Epub 2014 Nov 01.
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  16. Krahn LE, Hershner S, Loeding LD, Maski KP, Rifkin DI, Selim B, Watson NF. Quality measures for the care of patients with narcolepsy. J Clin Sleep Med. 2015 Mar 15; 11 (3):335
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  17. Chopra A, Selim B, Silber MH, Krahn L. Para-suicidal amnestic behavior associated with chronic zolpidem use: implications for patient safety. Psychosomatics. 2013 Sep-Oct; 54 (5):498-501 Epub 2013 Jan 22
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  18. Bright RP, Krahn L. Depression and suicide among physicians. Current Psychiatry. 2011; 10(4):16-30.
  19. Bright RP, Civalier KM, Krahn L. Reliability of self-reported nicotine use as determined by serum cotinine levels in patients referred for liver transplantation. Psychosomatics. 2010 Sep-Oct; 51(5):395-400.
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  20. Eleid MF, Krahn LE, Agrwal N, Goodman BP. Carisoprodol withdrawal after internet purchase. Neurologist. 2010 Jul; 16: (4)262-4.
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  21. Krahn LE, Bostwick JM, Stonnington CM. Looking toward DSM-V: should factitious disorder become a subtype of somatoform disorder? Psychosomatics. 2008 Jul-Aug; 49(4):277-82.
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  22. Krahn LE, Miller BW, Bergstrom LR. Rapid resolution of intense suicidal ideation after treatment of severe obstructive sleep apnea. J Clin Sleep Med. 2008 Feb 15; 4 (1):64-5
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  23. Driver-Dunckley ED, Noble BN, Hentz JG, Evidente VG, Caviness JN, Parish J, Krahn L, Adler CH. Gambling and increased sexual desire with dopaminergic medications in restless legs syndrome. Clin Neuropharmacol. 2007 Sep-Oct; 30 (5):249-55
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  24. Martin KA, Krahn LE, Balan V, Rosati MJ. Selective serotonin reuptake inhibitors in the context of hepatitis C infection: reexamining the risks of bleeding. J Clin Psychiatry. 2007 Jul; 68 (7):1024-6
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  25. Martin KA, Krahn LE, Balan V, Rosati MJ. Modafinil's use in combating interferon-induced fatigue. Dig Dis Sci. 2007 Apr; 52 (4):893-6 Epub 2007 Feb 21
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  26. Moore WR, Silber MH, Decker PA, Heim-Penokie PC, Sikkink VK, Slocumb N, Richardson JW, Krahn LE. Cataplexy Emotional Trigger Questionnaire (CETQ)--a brief patient screen to identify cataplexy in patients with narcolepsy. J Clin Sleep Med. 2007 Feb 15; 3 (1):37-40
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  27. Caselli RJ, Chen K, Bandy D, Smilovici O, Boeve BF, Osborne D, Alexander GE, Parish JM, Krahn LE, Reiman EM. A preliminary fluorodeoxyglucose positron emission tomography study in healthy adults reporting dream-enactment behavior. Sleep. 2006 Jul; 29 (7):927-33
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  28. Morgenthaler TI, Olson EJ, Gay P, Decker PA, Herold D, Moore W, Silber MH, Krahn L. Effect of a targeted obstructive sleep apnea consult to improve access and quality at a sleep disorders center. J Clin Sleep Med. 2006 Jan 15; 2(1):49-56.
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  29. Krahn LE, Lymp JF, Moore WR, Slocumb N, Silber MH. Characterizing the emotions that trigger cataplexy. J Neuropsychiatry Clin Neurosci. 2005 Winter; 17(1):45-50.
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  30. Krahn LE. Reevaluating spells initially identified as cataplexy. Sleep Med. 2005 Nov; 6(6):537-42.
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  31. Krahn LE, DiMartini A. Psychiatric and psychosocial aspects of liver transplantation. Liver Transpl. 2005 Oct; 11(10):1157-68.
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  32. Black JL 3rd, Silber MH, Krahn LE, Avula RK, Walker DL, Pankratz VS, Fredrickson PA, Slocumb NL. Studies of humoral immunity to preprohypocretin in human leukocyte antigen DQB1*0602-positive narcoleptic subjects with cataplexy. Biol Psychiatry. 2005 Sep 15; 58(6):504-9.
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  33. Wall CA, Rummans TA, Aksamit AJ, Krahn LE, Pankratz VS. Psychiatric manifestations of Creutzfeldt-Jakob disease: a 25-year analysis. J Neuropsychiatry Clin Neurosci. 2005 Fall; 17 (4):489-95
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  34. Auger RR, Goodman SH, Silber MH, Krahn LE, Pankratz VS, Slocumb NL. Risks of high-dose stimulants in the treatment of disorders of excessive somnolence: a case-control study. Sleep. 2005 Jun; 28 (6):667-72
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  35. Black JL 3rd, Silber MH, Krahn LE, Fredrickson PA, Pankratz VS, Avula R, Walker DL, Slocumb NL. Analysis of hypocretin (orexin) antibodies in patients with narcolepsy. Sleep. 2005 Apr; 28 (4):427-31
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  36. Krahn LE. Psychiatric disorders associated with disturbed sleep. Semin Neurol. 2005 Mar; 25 (1):90-6
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  37. Krahn LE. Out of the pipeline Eszopiclone. Current Psychiatry. 2005; 4(2):222-5.
  38. Krahn LE, Gonzalez-Arriaza HL. Narcolepsy with cataplexy. Am J Psychiatry. 2004 Dec; 161 (12):2181-4
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  39. Kotagal S, Krahn LE, Slocumb N. A putative link between childhood narcolepsy and obesity. Sleep Med. 2004 Mar; 5(2):147-50.
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  40. Nelson TK, Krahn LE. Treating affective illness in chronic pain:Comorbidity presents treatment challenges and opportunities. Current Psychiatry. 2004; 3(5):51-67.
  41. Krahn LE. Help night shift workers sleep properly. Current Psychiatry. 2004; 3.
  42. Krahn LE. Sleep disorders. Semin Neurol. 2003 Sep; 23(3):307-14.
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  43. Krahn LE, Li HZ, O'Connor MK. Patients who strive to be ill: Factitious disorder with physical symptoms. Am J Psychiatry. 2003 Jun; 160(6):1163-8.
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  44. Korndorfer SR, Lucas AR, Suman VJ, Crowson CS, Krahn LE, Melton LJ 3rd. Long-term survival of patients with anorexia nervosa: a population-based study in Rochester, Minn. Mayo Clin Proc. 2003 Mar; 78 (3):278-84
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  45. Krahn LE. Factitious disorder: managing patients who intend to be ill. Current Psychiatry. 2003; 2:47-56.
  46. Cox LS, Patten CA, Krahn LE, Hurt RD, Croghan IT, Wolter TD, Schroeder DR, Tri D, Offord KP. The effect of nicotine patch therapy on depression in nonsmokers: a preliminary study. J Addict Dis. 2003; 22 (4):75-85
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  47. Krahn LE. Out of the pipeline: Sodium Oxbate. Current Psychiatry. 2003; 2:123-6.
  48. Black JL 3rd, Krahn LE, Pankratz VS, Silber M. Search for neuron-specific and nonneuron-specific antibodies in narcoleptic patients with and without HLA DQB1*0602. Sleep. 2002 Nov 1; 25 (7):719-23
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  49. Krahn LE, Pankratz VS, Oliver L, Boeve BF, Silber MH. Hypocretin (orexin) levels in cerebrospinal fluid of patients with narcolepsy: relationship to cataplexy and HLA DQB1*0602 status. Sleep. 2002 Nov 1; 25 (7):733-6
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  50. Kung S, Mueller PS, Geda YE, Krahn LE. Delirium resulting from paraneoplastic limbic encephalitis caused by Hodgkin's disease. Psychosomatics. 2002 Nov-Dec; 43(6):498-501.
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  51. Krahn LE, Boeve BF, Oliver L, Silber MH. Hypocretin (orexin) and melatonin values in a narcoleptic-like sleep disorder after pinealectomy. Sleep Med. 2002 Nov; 3 (6):521-3
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  52. Silber MH, Krahn LE, Olson EJ, Pankratz VS. The epidemiology of narcolepsy in Olmsted County, Minnesota: a population-based study. Sleep. 2002 Mar 15; 25 (2):197-202
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  53. Silber MH, Krahn LE, Olson EJ. Diagnosing narcolepsy: validity and reliability of new diagnostic criteria. Sleep Med. 2002 Mar; 3 (2):109-13
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  54. Krahn LE, Bostwick JM, Sutor B, Olsen MW. The Challenge of Empathy: A Pilot Study of the Use of Standardized Patients to Teach Introductory Psychopathology to Medical Students. Acad Psychiatry. 2002 Mar; 26 (1):26-30
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  55. Krahn LE, Hansen MR, Tinsley JA. Psychiatric residents' exposure to the field of sleep medicine: A survey of psychiatric program directors. Academic Psychiatry. 2002; 26:253-6.
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  56. Lapid MI, Hall-Flavin DK, Cox LS, Lichty EJ, Krahn LE. Smokeless tobacco use among addiction patients: a brief report. J Addict Dis. 2002; 21(2):27-33.
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  57. Krahn LE. Enigmatic patients: factitious disorder with physical symptoms. Directions in Psychiatry. 2002; 22:217-23.
  58. Krahn LE. Excessive daytime sleepiness: a psychiatric perspective. Current Psychiatry. 2002; 1(1):49-57.
  59. Augustine K, Cameron B, Camp J, Krahn L, Robb R. An immersive simulation system for provoking and analyzing cataplexy. Stud Health Technol Inform. 2002; 85:31-7.
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  60. Malik S, Malik S, Boeve BF, Krahn LE, Silber MH. Narcolepsy associated with other central nervous system disorders. Neurology. 2001 Aug 14; 57 (3):539-41
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  61. Krahn LE, Hansen MR, Shepard JW. Pseudocataplexy. Psychosomatics. 2001 Jul-Aug; 42(4):356-8.
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  62. Black JL, Krahn LE, Jalal SM. Voltage-gated calcium channel gamma 2 subunit gene is not deleted in velo-cardio-facial syndrome. Mol Psychiatry. 2001 Jul; 6(4):461-4.
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  63. Zimmermann RC, Krahn LE, Klee GG, Ditkoff EC, Ory SJ, Sauer MV. Prolonged inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates the circadian rhythm of human TSH secretion. J Soc Gynecol Investig. 2001 May-Jun; 8(3):174-8.
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  64. Worrel LM, Krahn LE, Sletten CD, Pond GR. Treating fibromyalgia with a brief interdisciplinary program: initial outcomes and predictors of response. Mayo Clin Proc. 2001 Apr; 76(4):384-90.
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  65. Krahn LE, Black JL, Silber MH. Narcolepsy: new understanding of irresistible sleep. Mayo Clin Proc. 2001 Feb; 76(2):185-94.
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  66. Krahn LE, Hanson CA, Pileggi TS, Rummans TA. Electroconvulsive therapy and cardiovascular complications in patients taking trazodone for insomnia. J Clin Psychiatry. 2001 Feb; 62 (2):108-10
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  67. Krahn LE, Moore WR, Altchuler SI. Narcolepsy and obesity: remission of severe cataplexy with sibutramine. Sleep Med. 2001 Jan; 2 (1):63-65
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  68. Saad DA, Black JL 3rd, Krahn LE, Rummans TA. ECT post eye surgery: two cases and a review of the literature. J ECT. 2000 Dec; 16 (4):409-14
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  69. Krahn LE, Gleber E, Rummans TA, Pileggi TS, Lucas DL, Li H. The effects of electroconvulsive therapy on melatonin. J ECT. 2000 Dec; 16 (4):391-8
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  70. Gursky JT, Krahn LE. The effects of antidepressants on sleep: a review. Harv Rev Psychiatry. 2000 Dec; 8 (6):298-306
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  71. Krahn LE, Boeve BF, Olson EJ, Herold DL, Silber MH. A standardized test for cataplexy. Sleep Med. 2000 Apr 1; 1 (2):125-130
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  72. Krahn LE. Current issues in diagnosis and treatment of narcolepsy. Directions in Psychiatry. 2000; 20:255-64.
  73. Goodman JA, Krahn LE, Smith GE, Rummans TA, Pileggi TS. Patient satisfaction with electroconvulsive therapy. Mayo Clin Proc. 1999 Oct; 74(10):967-71.
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  74. Takahashi PY, Krahn L. Case report: delusions of parasitosis as an unusual presenting feature of dementia. Ann Long-Term Care,. 1999; 7: (4)153-5.
  75. Krahn LE, Lin SC, Klee GG, Lu PY, Ory SJ, Zimmermann RC. The effect of presynaptic catecholamine depletion on 6-hydroxymelatonin sulfate: a double blind study of alpha-methyl-para-tyrosine. Eur Neuropsychopharmacol. 1999 Jan; 9 (1-2):61-6
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  76. Krahn LE, Maraganore DM, Michels VV. Childhood-onset schizophrenia associated with parkinsonism in a patient with a microdeletion of chromosome 22. Mayo Clin Proc. 1998 Oct; 73 (10):956-9
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  77. Krahn LE, Santoscoy G, Van Loon JA. A schizophrenic patient's attempt to resume dialysis following renal transplantation. Psychosomatics. 1998 Sep-Oct; 39(5):470-3.
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  78. Zimmermann RC, Krahn L, Rahmanie N, Sauer MV. Prolonged inhibition of presynaptic catecholamine synthesis does not alter leptin secretion in normal-weight men women. Hum Reprod. 1998 Apr; 13(4):822-825.
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  79. Sutor B, Rummans TA, Jowsey SG, Krahn LE, Martin MJ, O'Connor MK, Philbrick KL, Richardson JW. Major depression in medically ill patients. Mayo Clin Proc. 1998 Apr; 73 (4):329-37
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  80. Krahn LE, Lin SC, Wisbey J, Rummans TA, O'Connor MK, O'Connor MK. Assessing sleep in psychiatric inpatients: nurse and patient reports versus wrist actigraphy. Ann Clin Psychiatry. 1997 Dec; 9 (4):203-10
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  81. Krahn LE, Reese MM, Rummans TA, Peterson GC, Suman VJ, Sharbrough FW, Cascino GD. Health care utilization of patients with psychogenic nonepileptic seizures. Psychosomatics. 1997 Nov-Dec; 38 (6):535-42
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  82. Krahn LE, Lee J, Richardson JW, Martin MJ, O'Connor MK, O'Connor MK. Hypokalemia leading to torsades de pointes. Munchausen's disorder or bulimia nervosa? Gen Hosp Psychiatry. 1997 Sep; 19 (5):370-7
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  83. MacMorran WS, Krahn LE. Adverse cutaneous reactions to psychotropic drugs. Psychosomatics. 1997 Sep-Oct; 38(5):413-22.
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  84. Krahn LE, Rummans TA, Peterson GC. Psychiatric implications of surgical treatment of epilepsy. Mayo Clin Proc. 1996 Dec; 71 (12):1201-4
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  85. Reeves AL, So EL, Sharbrough FW, Krahn LE. Movement disorders associated with the use of gabapentin. Epilepsia. 1996 Oct; 37 (10):988-90
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  86. Krahn LE, Lu PY, Klee G, Delgado PR, Lin SC, Zimmermann RC. Examining serotonin function: a modified technique for rapid tryptophan depletion. Neuropsychopharmacology. 1996 Oct; 15(4):325-8.
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  87. Zimmermann RC, Krahn L, Klee G, Lu PY, Ory SJ, Lin SC. The impact of gender on alpha-methyl-para-tyrosine mediated changes in prolactin secretion and 6-hydroxymelatonin sulfate excretion. Psychoneuroendocrinology. 1996 Jul; 21 (5):469-78
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  88. Rummans TA, Evans JM, Krahn LE, Fleming KC. Delirium in elderly patients: evaluation and management. Mayo Clin Proc. 1995 Oct; 70 (10):989-98
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  89. Krahn LE, Rummans TA, Sharbrough FW, Jowsey SG, Cascino GD. Pseudoseizures after epilepsy surgery. Psychosomatics. 1995 Sep-Oct; 36(5):487-93.
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  90. Epstein SA, Krahn L, Clauw DJ, Gomes AP, Weigert S, Goldberg RL. Psychiatric aspects of the eosinophilia-myalgia syndrome. Psychosomatics. 1995 Jan-Feb; 36(1):22-5.
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  91. Zimmermann RC, Krahn L, Klee G, Delgado P, Ory SJ, Lin SC. Inhibition of presynaptic catecholamine synthesis with alpha-methyl-para-tyrosine attenuates nocturnal melatonin secretion in humans. J Clin Endocrinol Metab. 1994 Oct; 79 (4):1110-4
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  92. Krahn LE, Goldberg RL. Psychotropic medications and the skin. Adv Psychosom Med. 1994; 21:90-106
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  93. Krahn LE, Rummans TA, Peterson GC, Cascino GD, Sharbrough FW. Electroconvulsive Therapy for Depression After Temporal Lobectomy for Epilepsy. Convuls Ther. 1993; 9 (3):217-219
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  94. Cohen CG, Krahn L, Wise TN, Epstein S, Ross R. Delusions of disfigurement in a woman with acne rosacea. Gen Hosp Psychiatry. 1991 Jul; 13(4):273-7.
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