Robert P. Frantz, M.D.

  1. Cardiologist
  2. Internist
  1. Reddy YNV, Frantz RP, Hassoun PM, Hemnes AR, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Finet JE, Jellis CL, Mathai SC, Tang WHW, Borlaug BA. Clinical Implications of Pretest Probability of HFpEF on Outcomes in Precapillary Pulmonary Hypertension. J Am Coll Cardiol. 2024 Oct 15 [Epub ahead of print]
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  2. Dardi F, Boucly A, Benza R, Frantz R, Mercurio V, Olschewski H, Radegran G, Rubin LJ, Hoeper MM. Risk stratification and treatment goals in pulmonary arterial hypertension. Eur Respir J. 2024 Oct; 64 (4) Epub 2024 Oct 31
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  3. Chan SY, Jose A, Tello K, Yogeswaran A, Majeed RW, Kiely DG, Lawrie A, Brittain E, Annis JS, Olschewski H, Kovacs G, Hassoun PM, Balasubramanian A, Konswa Z, Sweatt AJ, Zamanian RT, Wilkins MR, Howard L, Arvanitaki A, Giannakoulas G, Cajigas HR, Frantz R, Williams PG, Frauendorf M, Marquardt K, Antoine T, Fuenderich M, Richter M, Grimminger F, Ghofrani HA, Wilhelm J, Seeger W, Pulmonary Vascular Research Institute GoDeep Consortium. Phosphodiesterase 5 Inhibitor Treatment Is Associated With Improved Survival in Pulmonary Hypertension Associated With COPD in the Pulmonary Vascular Research Institute GoDeep Meta-Registry. Chest. 2024 Sep 7 Epub 2024 Sept 07
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  4. Jose A, Yogeswaran A, Gall H, Funderich M, Wilkins MR, Howard L, Kiely DG, Lawrie A, Hassoun PM, Sirenklo Y, Torbas O, Sweatt AJ, Zamanian RT, Williams PG, Frauendorf M, Arvanitaki A, Giannakoulas G, Saleh K, Sabbour H, Cajigas HR, Frantz R, Al Ghouleh I, Chan SY, Brittain E, Annis JS, Pepe A, Ghio S, Orfanos S, Anthi A, Majeed RW, Wilhelm J, Ghofrani HA, Richter MJ, Grimminger F, Sahay S, Tello K, Seeger W, Pulmonary Vascular Research Institute GoDeep Consortium. Comparison of Contemporary Risk Scores in All Groups of Pulmonary Hypertension: A Pulmonary Vascular Research Institute GoDeep Meta-Registry Analysis. Chest. 2024 Sep; 166 (3):585-603 Epub 2024 Mar 19
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  5. Reddy YNV, Dubrock H, Hassoun PM, Hemnes A, Horn E, Leopold JA, Rischard F, Rosenzweig EB, Hill NS, Erzurum SC, Beck GJ, Mathai SC, Mukherjee M, Tang WHW, Borlaug BA, Frantz RP, and the PVDOMICS Study Group. Non-invasive prediction of pulmonary vascular disease-related exercise intolerance and survival in non-group 1 pulmonary hypertension. Eur J Heart Fail. 2024 Jul 26 Epub 2024 July 26
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  6. Inglis SS, Kanwar A, Bonilla HG, Singh S, Pearson JY, Abbas M, Folkens LA, Ou NN, Spencer PJ, Villavicencio MA, Clavell AL, Frantz RP, Rosenbaum AN, Behfar A. Reduction in Balloon Pump Size Reduces Axillary Intraaortic Balloon Pump Failure Risk. ASAIO J. 2024 Jul 9 Epub 2024 July 09
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  7. Borlaug BA, Larive B, Frantz RP, Hassoun P, Hemnes A, Horn E, Leopold J, Rischard F, Berman-Rosenzweig E, Beck G, Erzurum S, Farha S, Finet JE, Highland KB, Jacob M, Jellis C, Mehra R, Renapurkar R, Singh H, Tang WHW, Vanderpool R, Wilcox J, Yu S, Hill N. Pulmonary hypertension across the spectrum of left heart and lung disease. Eur J Heart Fail. 2024 Jul; 26 (7):1642-1651 Epub 2024 June 04
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  8. Frantz RP, McLaughlin VV, Sahay S, Escribano Subias P, Zolty RL, Benza RL, Channick RN, Chin KM, Hemnes AR, Howard LS, Sitbon O, Vachiery JL, Zamanian RT, Cravets M, Roscigno RF, Mottola D, Osterhout R, Bruey JM, Elman E, Tompkins CA, Parsley E, Aranda R, Zisman LS, Ghofrani HA, TORREY Study Investigators. Seralutinib in adults with pulmonary arterial hypertension (TORREY): a randomised, double-blind, placebo-controlled phase 2 trial. Lancet Respir Med. 2024 Jul; 12 (7):523-534 Epub 2024 May 02
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  9. DuBrock HM, Wagner TE, Carlson K, Carpenter CL, Awasthi S, Attia ZI, Frantz RP, Friedman PA, Kapa S, Annis J, Brittain EL, Hemnes AR, Asirvatham SJ, Babu M, Prasad A, Yoo U, Barve R, Selej M, Agron P, Kogan E, Quinn D, Dunnmon P, Khan N, Soundararajan V. An electrocardiogram-based AI algorithm for early detection of pulmonary hypertension. Eur Respir J. 2024 Jul; 64 (1) Epub 2024 July 25
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  10. Balasubramanian A, Larive AB, Horn EM, DuBrock HM, Mehra R, Jacob MS, Hemnes AR, Leopold JA, Radeva MK, Hill NS, Erzurum SC, Rosenzweig EB, Frantz RP, Rischard FP, Beck GJ, Hassoun PM, Mathai SC, PVDOMICS Study Group. Health-Related Quality of Life Across the Spectrum of Pulmonary Hypertension. Chest. 2024 Jun; 165 (6):1493-1504 Epub 2024 Feb 12
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  11. Bailey ME, Durst L, Cajigas HR, Kane GC, Krowka MJ, Kushwaha SS, McCully RB, Murphy JG, Reddy YN, Frantz RP, DuBrock HM. Using PAH-SYMPACT to assess quality of life in patients with pulmonary hypertension associated with chronic lung disease. Pulm Circ. 2024 Jan; 14 (1):e12343 Epub 2024 Feb 10
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  12. Del Valle KT, Krowka MJ, Schinstock CA, Nath KA, Burger CD, Reddy YN, Frantz RP, Prakash YS, DuBrock HM. Hemodynamic response to inhaled nitric oxide in patients with pulmonary hypertension and chronic kidney disease: A retrospective cohort study. Pulm Circ. 2024 Jan; 14 (1):e12341 Epub 2024 Feb 10
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  13. DuBrock HM, Germack HD, Gauthier-Loiselle M, Linder J, Satija A, Manceur AM, Cloutier M, Lefebvre P, Panjabi S, Frantz RP. Economic Burden of Delayed Diagnosis in Patients with Pulmonary Arterial Hypertension (PAH). Pharmacoecon Open. 2024 Jan; 8 (1):133-146 Epub 2023 Nov 18
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  14. Lowery MM, Hill NS, Wang L, Rosenzweig EB, Bhat A, Erzurum S, Finet JE, Jellis CL, Kaur S, Kwon DH, Nawabit R, Radeva M, Beck GJ, Frantz RP, Hassoun PM, Hemnes AR, Horn EM, Leopold JA, Rischard FP, Mehra R, Pulmonary Vascular Disease Phenomics (PVDOMICS) Study Group. Sleep-Related Hypoxia, Right Ventricular Dysfunction, and Survival in Patients With Group 1 Pulmonary Arterial Hypertension. J Am Coll Cardiol. 2023 Nov 21; 82 (21):1989-2005
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  15. Simpson CE, Ambade AS, Harlan R, Roux A, Aja S, Graham D, Shah AA, Hummers LK, Hemnes AR, Leopold JA, Horn EM, Berman-Rosenzweig ES, Grunig G, Aldred MA, Barnard J, Comhair SAA, Tang WHW, Griffiths M, Rischard F, Frantz RP, Erzurum SC, Beck GJ, Hill NS, Mathai SC, Hassoun PM, Damico RL, the PVDOMICS Study Group. Kynurenine pathway metabolism evolves with development of preclinical and scleroderma-associated pulmonary arterial hypertension. Am J Physiol Lung Cell Mol Physiol. 2023 Nov 1; 325 (5):L617-L627 Epub 2023 Oct 03
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  16. Miranda WR, Charles Jain C, Frantz RP, DuBrock HM, Connolly HM, Burchill LJ, Egbe AC. Effects of inhaled nitric oxide on Fontan hemodynamics in adults. J Heart Lung Transplant. 2023 Oct; 42 (10):1349-1352 Epub 2023 Apr 29
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  17. Rischard FP, Bernardo RJ, Vanderpool RR, Kwon DH, Acharya T, Park MM, Katrynuik A, Insel M, Kubba S, Badagliacca R, Larive AB, Naeije R, Garcia JGN, Beck GJ, Erzurum SC, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Leopold JA, Rosenzweig EB, Tang WHW, Wilcox JD. Classification and Predictors of Right Ventricular Functional Recovery in Pulmonary Arterial Hypertension. Circ Heart Fail. 2023 Oct; 16 (10):e010555 Epub 2023 Sept 04
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  18. Frantz RP. Group 2 pulmonary hypertension: from diagnosis to treatment. Current Opinion in Pulmonary Medicine. 2023 Sep; 29 (5):391-8
  19. Naranjo M, Rosenzweig EB, Hemnes AR, Jacob M, Desai A, Hill NS, Larive AB, Finet JE, Leopold J, Horn E, Frantz R, Rischard F, Erzurum S, Beck G, Mathai SC, Hassoun PM, PVDOMICS Study Group. Frequency of acute vasodilator response (AVR) in incident and prevalent patients with pulmonary arterial hypertension: Results from the pulmonary vascular disease phenomics study. Pulm Circ. 2023 Jul; 13 (3):e12281 Epub 2023 Aug 21
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  20. Farber HW, Chakinala MM, Cho M, Frantz RP, Frick A, Lancaster L, Milligan S, Oudiz R, Panjabi S, Tsang Y, Nathan SD. Characteristics of patients with pulmonary arterial hypertension from an innovative, comprehensive real-world patient data repository. Pulm Circ. 2023 Jul; 13 (3):e12258 Epub 2023 July 06
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  21. Forfia P, Benza R, D'Alto M, De Marco T, Elwing JM, Frantz R, Haddad F, Oudiz R, Preston IR, Rosenkranz S, Ryan J, Schilz R, Shlobin OA, Vachiery JL, Vizza CD, Vonk Noordegraaf A, Sketch MR, Broderick M, McLaughlin V. The heart of the matter: Right heart imaging indicators for treatment escalation in pulmonary arterial hypertension. Pulm Circ. 2023 Apr; 13 (2):e12240 Epub 2023 May 21
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  22. Howard LS, Rosenkranz S, Frantz RP, Hemnes AR, Pfister T, Hsu Schmitz SF, Skara H, Humbert M, Preston IR. Assessing Daily Life Physical Activity by Actigraphy in Pulmonary Arterial Hypertension: Insights From the Randomized Controlled Study With Selexipag (TRACE). Chest. 2023 Feb; 163 (2):407-418 Epub 2022 Sept 08
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  23. Rohlfing AB, Bischoff KE, Kolaitis NA, Kronmal RA, Kime NA, Gray MP, Bartolome S, Chakinala MM, Frantz RP, Ventetuolo CE, Mathai SC, De Marco T, PHAR investigators. Palliative care referrals in patients with pulmonary arterial hypertension: The Pulmonary Hypertension Association Registry. Respir Med. 2023 Jan; 206:107066 Epub 2022 Nov 30
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  24. Anand V, Covington MK, Saraswati U, Scott CG, Lee AT, Frantz RP, Anavekar NS, Geske JB, Arruda-Olson AM, Klarich KW. Prevalence, sex differences, and implications of pulmonary hypertension in patients with apical hypertrophic cardiomyopathy. Front Cardiovasc Med. 2023; 10:1288747 Epub 2024 Jan 11
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  25. Frantz RP, Leopold JA, Hassoun PM, Hemnes AR, Horn EM, Mathai SC, Rischard FP, Larive AB, Tang WHW, Park MM, Hill NS, Rosenzweig EB. Acute vasoreactivity testing during right heart catheterization in chronic thromboembolic pulmonary hypertension: Results from the pulmonary vascular disease phenomics study. Pulm Circ. 2023 Jan; 13 (1):e12181 Epub 2023 Jan 06
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  26. DuBrock HM, Reddy YN, Durst LA, Schroeder DR, Park G, Cajigas HR, Kane GC, Kushwaha SS, McCully RB, Murphy JG, Anand V, Krowka MJ, Frantz RP. The feasibility and value of assessing patient-reported outcomes in pulmonary arterial hypertension. Pulm Circ. 2022 Oct; 12 (4):e12143 Epub 2022 Oct 01
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  27. DuBrock HM, Burger CD, Bartolome SD, Feldman JP, Ivy DD, Rosenzweig EB, Sager JS, Presberg KW, Mathai SC, Lammi MR, Klinger JR, Eggert M, De Marco T, Elwing JM, Badesch D, Bull TM, Cadaret LM, Ramani G, Thenappan T, Ford HJ, Al-Naamani N, Simon MA, Mazimba S, Runo JR, Chakinala M, Horn EM, Ryan JJ, Frantz RP, Krowka MJ, PHAR Investigators. Erratum: Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: An analysis of the Pulmonary Hypertension Association Registry. Pulm Circ. 2022 Oct; 12 (4):e12172 Epub 2022 Dec 15
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  28. McLaughlin VV, Channick R, Kim NH, Frantz RP, McConnell JW, Melendres-Groves L, Miller C, Ravichandran A, Rodriguez-Lopez J, Brand M, Leroy S, Wetherill G, Chin KM. Safety of macitentan for the treatment of pulmonary hypertension: Real-world experience from the OPsumit(R) USers Registry (OPUS) and OPsumit(R) Historical USers cohort (OrPHeUS). Pulm Circ. 2022 Oct; 12 (4):e12150 Epub 2022 Oct 01
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  29. Hemnes AR, Leopold JA, Radeva MK, Beck GJ, Abidov A, Aldred MA, Barnard J, Rosenzweig EB, Borlaug BA, Chung WK, Comhair SAA, Desai AA, Dubrock HM, Erzurum SC, Finet JE, Frantz RP, Garcia JGN, Geraci MW, Gray MP, Grunig G, Hassoun PM, Highland KB, Hill NS, Hu B, Kwon DH, Jacob MS, Jellis CL, Larive AB, Lempel JK, Maron BA, Mathai SC, McCarthy K, Mehra R, Nawabit R, Newman JH, Olman MA, Park MM, Ramos JA, Renapurkar RD, Rischard FP, Sherer SG, Tang WHW, Thomas JD, Vanderpool RR, Waxman AB, Wilcox JD, Yuan JX, Horn EM, PVDOMICS Study Group. Clinical Characteristics and Transplant-Free Survival Across the Spectrum of Pulmonary Vascular Disease. J Am Coll Cardiol. 2022 Aug 16; 80 (7):697-718
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  30. Schettle S, Frantz R, Stulak J, Villavicencio M, Rosenbaum A. HeartWare Thrombosis After mRNA COVID-19 Vaccination. Mayo Clin Proc 2022 Jul; 97 (7):1399-1401 Epub 2022 May 17
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  31. Majeed RW, Wilkins MR, Howard L, Hassoun PM, Anthi A, Cajigas HR, Cannon J, Chan SY, Damonte V, Elwing J, Forster K, Frantz R, Ghio S, Al Ghouleh I, Hilgendorff A, Jose A, Juaneda E, Kiely DG, Lawrie A, Orfanos SE, Pepe A, Pepke-Zaba J, Sirenko Y, Swett AJ, Torbas O, Zamanian RT, Marquardt K, Michel-Backofen A, Antoine T, Wilhelm J, Barwick S, Krieb P, Fuenderich M, Fischer P, Gall H, Ghofrani HA, Grimminger F, Tello K, Richter MJ, Seeger W. Pulmonary Vascular Research Institute GoDeep: A meta-registry merging deep phenotyping datafrom international PH reference centers. Pulm Circ. 2022 Jul; 12 (3):e12123 Epub 2022 July 01
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  32. Hill NS, Feldman JP, Sahay S, Benza RL, Preston IR, Badesch D, Frantz RP, Patel S, Galloway A, Bull TM, INSPIRE study investigators. INSPIRE: Safety and tolerability of inhaled Yutrepia (treprostinil) in pulmonary arterial hypertension (PAH). Pulm Circ. 2022 Jul; 12 (3):e12119 Epub 2022 July 01
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  33. Jellis CL, Park MM, Abidov A, Borlaug BA, Brittain EL, Frantz R, Hassoun PM, Horn EM, Jaber WA, Jiwon K, Karas MG, Kwon D, Leopold JA, Maron B, Mathai SC, Mehra R, Rischard F, Rosenzweig EB, Tang WHW, Vanderpool R, Thomas JD, PVDOMICS Study Group. Comprehensive echocardiographic evaluation of the right heart in patients with pulmonary vascular diseases: the PVDOMICS experience. Eur Heart J Cardiovasc Imaging. 2022 Jun 21; 23 (7):958-969
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  34. Chang KY, Duval S, Badesch DB, Bull TM, Chakinala MM, De Marco T, Frantz RP, Hemnes A, Mathai SC, Rosenzweig EB, Ryan JJ, Thenappan T, PHAR Investigators *. Mortality in Pulmonary Arterial Hypertension in the Modern Era: Early Insights From the Pulmonary Hypertension Association Registry. J Am Heart Assoc. 2022 May 3; 11 (9):e024969 Epub 2022 Apr 27
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  35. Vizza CD, Lang IM, Badagliacca R, Benza RL, Rosenkranz S, White RJ, Adir Y, Andreassen AK, Balasubramanian V, Bartolome S, Blanco I, Bourge RC, Carlsen J, Camacho REC, D'Alto M, Farber HW, Frantz RP, Ford HJ, Ghio S, Gomberg-Maitland M, Humbert M, Naeije R, Orfanos SE, Oudiz RJ, Perrone SV, Shlobin OA, Simon MA, Sitbon O, Torres F, Luc Vachiery J, Wang KY, Yacoub MH, Liu Y, Golden G, Matsubara H. Aggressive Afterload Lowering to Improve the Right Ventricle: A New Target for Medical Therapy in Pulmonary Arterial Hypertension? Am J Respir Crit Care Med. 2022 Apr 1; 205 (7):751-760
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  36. Anderson JH, Cabalka AK, Frantz RP, Cajigas HR, Taggart NW. Transcatheter Nonductal Reverse Potts Shunt Creation in Pulmonary Arterial Hypertension. Circ Cardiovasc Interv. 2022 Jan; 15 (1):e011315 Epub 2021 Dec 21
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  37. Rosenkranz S, Feldman J, McLaughlin VV, Rischard F, Lange TJ, White RJ, Peacock AJ, Gerhardt F, Ebrahimi R, Brooks G, Satler C, Frantz RP, ARROW Study Group. Selonsertib in adults with pulmonary arterial hypertension (ARROW): a randomised, double-blind, placebo-controlled, phase 2 trial. Lancet Respir Med. 2022 Jan; 10 (1):35-46 Epub 2021 Aug 20
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  38. McGlothlin DP, Granton J, Klepetko W, Beghetti M, Rosenzweig EB, Corris PA, Horn E, Kanwar MK, McRae K, Roman A, Tedford R, Badagliacca R, Bartolome S, Benza R, Caccamo M, Cogswell R, Dewachter C, Donahoe L, Fadel E, Farber HW, Feinstein J, Franco V, Frantz R, Gatzoulis M, Guazzi M, Hansmann G, Hastings S, Heerdt PM, Hemnes A, Herpain A, Hsu CH, Kerr K, Kolaitis NA, Kukreja J, Madani M, McCluskey S, McCulloch M, Moser B, Navaratnam M, Reimer C, Savale L, Shlobin OA, Svetlichnaya J, Swetz K, Tashjian J, Thenappan T, Vizza CD, West S, Zuckerman W, Zuckermann A, De Marco T. ISHLT consensus statement: perioperative management of patients with pulmonary hypertension and right heart failure undergoing surgery. Journal of Heart and Lung Transplantation. 2022; 41 (9):1135-94
  39. Burger CD, DuBrock HM, Cartin-Ceba R, Moss JE, Shapiro BP, Frantz RP. Topic-Based, Recent Literature Review on Pulmonary Hypertension. Mayo Clin Proc. 2021 Dec; 96 (12):3109-3121 Epub 2021 Aug 31
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  40. de Perrot M, Gopalan D, Jenkins D, Lang IM, Fadel E, Delcroix M, Benza R, Heresi GA, Kanwar M, Granton JT, McInnis M, Klok FA, Kerr KM, Pepke-Zaba J, Toshner M, Bykova A, Armini AM, Robbins IM, Madani M, McGiffin D, Wiedenroth CB, Mafeld S, Opitz I, Mercier O, Uber PA, Frantz RP, Auger WR. Evaluation and management of patients with chronic thromboembolic pulmonary hypertension - consensus statement from the ISHLT. J Heart Lung Transplant. 2021 Nov; 40 (11):1301-1326 Epub 2021 Aug 03
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  41. Frantz RP, Benza RL, Channick RN, Chin K, Howard LS, McLaughlin VV, Sitbon O, Zamanian RT, Hemnes AR, Cravets M, Bruey JM, Roscigno R, Mottola D, Elman E, Zisman LS, Ghofrani HA. TORREY, a Phase 2 study to evaluate the efficacy and safety of inhaled seralutinib for the treatment of pulmonary arterial hypertension. Pulm Circ. 2021 Oct-Dec; 11 (4):20458940211057071 Epub 2021 Nov 11
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  42. Morland K, Raina A, Nails A, Classi P, Etschmaier M, Frantz RP. Reasons for refusing parenteral therapy: a qualitative study of patients with pulmonary arterial hypertension. Pulm Circ. 2021 Oct-Dec; 11 (4):20458940211046761 Epub 2021 Dec 13
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  43. DuBrock HM, Burger CD, Bartolome SD, Feldman JP, Ivy DD, Rosenzweig EB, Sager JS, Presberg KW, Mathai SC, Lammi MR, Klinger JR, Eggert M, De Marco T, Elwing JM, Badesch D, Bull TM, Cadaret LM, Ramani G, Thenappan T, Ford HJ, Al-Naamani N, Simon MA, Mazimba S, Runo JR, Chakinala M, Horn EM, Ryan JJ, Frantz RP, Krowka MJ. Health disparities and treatment approaches in portopulmonary hypertension and idiopathic pulmonary arterial hypertension: an analysis of the Pulmonary Hypertension Association Registry. Pulm Circ. 2021 Jul-Sep; 11 (3):20458940211020913 Epub 2021 May 17
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  44. Maron BA, Abman SH, Elliott CG, Frantz RP, Hopper RK, Horn EM, Nicolls MR, Shlobin OA, Shah SJ, Kovacs G, Olschewski H, Rosenzweig EB. Pulmonary Arterial Hypertension: Diagnosis, Treatment, and Novel Advances. Am J Respir Crit Care Med. 2021 Jun 15; 203 (12):1472-1487
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  45. Frantz RP. REPLACE and the role of riociguat in pulmonary arterial hypertension therapy. Lancet Respir Med 2021 Jun; 9 (6):546-547 Epub 2021 Mar 24
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  46. Vallabhajosyula S, Shankar A, Vojjini R, Cheungpasitporn W, Sundaragiri PR, DuBrock HM, Sekiguchi H, Frantz RP, Cajigas HR, Kane GC, Oh JK. Impact of Right Ventricular Dysfunction on Short-term and Long-term Mortality in Sepsis: A Meta-analysis of 1,373 Patients. Chest. 2021 Jun; 159 (6):2254-2263 Epub 2021 Feb 27
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  47. Daly RC, Rosenbaum AN, Dearani JA, Clavell AL, Pereira NL, Boilson BA, Frantz RP, Behfar A, Dunlay SM, Rodeheffer RJ, Schirger JA, Taner T, Gandhi MJ, Heimbach JK, Rosen CB, Edwards BS, Kushwaha SS. Heart-After-Liver Transplantation Attenuates Rejection of Cardiac Allografts in Sensitized Patients. J Am Coll Cardiol. 2021 Mar 16; 77 (10):1331-1340
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  48. Min J, Badesch D, Chakinala M, Elwing J, Frantz R, Horn E, Klinger J, Lammi M, Mazimba S, Sager J, Shlobin O, Simon M, Thenappan T, Grinnan D, Ventetuolo C, Al-Naamani N, PHAR Investigators. Prediction of Health-related Quality of Life and Hospitalization in Pulmonary Arterial Hypertension: The Pulmonary Hypertension Association Registry. Am J Respir Crit Care Med 2021 Mar 15; 203 (6):761-764
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  49. Borgese M, Badesch D, Bull T, Chakinala M, DeMarco T, Feldman J, Ford HJ, Grinnan D, Klinger JR, Bolivar L, Shlobin OA, Frantz RP, Sager JS, Mathai SC, Kawut S, Leary PJ, Gray MP, Popat RA, Zamanian RT, PHAR Study Group. EmPHasis-10 as a measure of health-related quality of life in pulmonary arterial hypertension: data from PHAR. Eur Respir J. 2021 Feb; 57 (2) Epub 2021 Feb 25
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  50. Anand V, Vallabhajosyula S, Cheungpasitporn W, Frantz RP, Cajigas HR, Strand JJ, DuBrock HM. Inpatient Palliative Care Use in Patients With Pulmonary Arterial Hypertension: Temporal Trends, Predictors, and Outcomes. Chest. 2020 Dec; 158 (6):2568-2578 Epub 2020 Aug 12
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  51. Chalmers SJ, Murphy SJ, Thompson LL, Hoppman NL, Smadbeck JB, Balcom JR, Harris FR, Frantz RP, Vasmatzis G, E Wylam M. Mate-pair sequencing identifies a cryptic BMPR2 mutation in hereditary pulmonary arterial hypertension. Pulm Circ. 2020 Jul-Sep; 10 (3):2045894020933081 Epub 2021 July 12
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  52. Deljou A, Sabov M, Kane GC, Frantz RP, DuBrock HM, Martin DP, Schroeder DR, Johnson MQ, Weingarten TN, Sprung J. Outcomes After Noncardiac Surgery for Patients with Pulmonary Hypertension: A Historical Cohort Study. J Cardiothorac Vasc Anesth. 2020 Jun; 34 (6):1506-1513 Epub 2019 Nov 09
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  53. McLaughlin VV, Channick R, De Marco T, Farber HW, Gaine S, Galie N, Krasuski RA, Preston I, Souza R, Coghlan JG, Frantz RP, Hemnes A, Kim NH, Lang IM, Langleben D, Li M, Sitbon O, Tapson V, Frost A. Results of an Expert Consensus Survey on the Treatment of Pulmonary Arterial Hypertension With Oral Prostacyclin Pathway Agents. Chest. 2020 Apr; 157 (4):955-965 Epub 2019 Nov 16
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  54. Steadman JA, Stulak JM, Clavell AL, Kushwaha SS, Edwards BS, Pereira NL, Dunlay SM, Schirger JA, Frantz RP, Smith BH, Dean PG, Daly RC. Combined Heart-Kidney Transplantation: Vasoplegia is Associated with Poorer Post-Kidney Transplant Outcomes. J Heart Lung Transplant. 2020 Apr; 39 (4S):S267 Epub 2020 Mar 30
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  55. Frantz RP, Chin KM, Zhao C, Flynn M, Badesch D. Pulmonary Arterial Hypertension-Symptoms and Impact Questionnaire: feasibility of utilizing one-day versus seven-day symptom reporting. Pulm Circ. 2020 Apr-Jun; 10 (2):2045894020923957 Epub 2020 May 14
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  56. Tang WHW, Wilcox JD, Jacob MS, Rosenzweig EB, Borlaug BA, Frantz RP, Hassoun PM, Hemnes AR, Hill NS, Horn EM, Singh HS, Systrom DM, Tedford RJ, Vanderpool RR, Waxman AB, Xiao L, Leopold JA, Rischard FP. Comprehensive Diagnostic Evaluation of Cardiovascular Physiology in Patients With Pulmonary Vascular Disease: Insights From the PVDOMICS Program. Circ Heart Fail. 2020 Mar; 13 (3):e006363 Epub 2020 Feb 24
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  57. Frantz RP, Hill JW, Lickert CA, Wade RL, Cole MR, Tsang Y, Drake W 3rd. Medication adherence, hospitalization, and healthcare resource utilization and costs in patients with pulmonary arterial hypertension treated with endothelin receptor antagonists or phosphodiesterase type-5 inhibitors. Pulm Circ. 2020 Jan-Mar; 10 (1):2045894019880086 Epub 2020 Mar 18
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  58. Asleh R, Alnsasra H, Daly RC, Schettle SD, Briasoulis A, Taher R, Dunlay SM, Stulak JM, Behfar A, Pereira NL, Frantz RP, Edwards BS, Clavell AL, Kushwaha SS. Predictors and Clinical Outcomes of Vasoplegia in Patients Bridged to Heart Transplantation With Continuous-Flow Left Ventricular Assist Devices. J Am Heart Assoc. 2019 Nov 19; 8 (22):e013108 Epub 2019 Nov 08
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  59. Gomberg-Maitland M, Bourge RC, Shapiro SM, Tarver JH 3rd, Zwicke DL, Feldman JP, Chakinala MM, Frantz RP, Torres F, Bag R, Murphy JA, Lautenbach AA, Morris M, Peterson L, Waxman AB. Long-term results of the DelIVery for Pulmonary Arterial Hypertension trial. Pulm Circ. 2019 Oct-Dec; 9 (4):2045894019878615 Epub 2019 Nov 05
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  60. Anand V, Frantz RP, DuBrock H, Kane GC, Krowka M, Yanagisawa R, Sandhu GS. Balloon Pulmonary Angioplasty for Chronic Thromboembolic Pulmonary Hypertension: Initial Single-Center Experience. Mayo Clin Proc Innov Qual Outcomes. 2019 Sep; 3 (3):311-318 Epub 2019 Aug 23
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  61. Alnsasra H, Asleh R, Schettle SD, Pereira NL, Frantz RP, Edwards BS, Clavell AL, Maltais S, Daly RC, Stulak JM, Rosenbaum AN, Behfar A, Kushwaha SS. Diastolic Pulmonary Gradient as a Predictor of Right Ventricular Failure After Left Ventricular Assist Device Implantation. J Am Heart Assoc. 2019 Aug 20; 8(16):e012073. Epub 2019 Aug 14.
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  62. Benza RL, Gomberg-Maitland M, Elliott CG, Farber HW, Foreman AJ, Frost AE, McGoon MD, Pasta DJ, Selej M, Burger CD, Frantz RP. Predicting Survival in Patients With Pulmonary Arterial Hypertension: The REVEAL Risk Score Calculator 2.0 and Comparison With ESC/ERS-Based Risk Assessment Strategies. Chest. 2019 Aug; 156 (2):323-337 Epub 2019 Feb 14
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  144. Frantz RP. Bosentan for pulmonary hypertension and other pulmonary diseases: emerging evidence. Future Cardiol. 2008 Sep; 4(5):459-68.
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  145. Lacy MQ, Dispenzieri A, Hayman SR, Kumar S, Kyle RA, Rajkumar SV, Edwards BS, Rodeheffer RJ, Frantz RP, Kushwaha SS, Clavell AL, Dearani JA, Sundt TM, Daly RC, McGregor CG, Gastineau DA, Litzow MR, Gertz MA. Autologous stem cell transplant after heart transplant for light chain (Al) amyloid cardiomyopathy. J Heart Lung Transplant. 2008 Aug; 27 (8):823-9 Epub 2008 July 03
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  147. Snyder EM, Olson TP, Johnson BD, Frantz RP. Influence of sildenafil on lung diffusion during exposure to acute hypoxia at rest and during exercise in healthy humans. Eur J Appl Physiol. 2008 Jul; 103(4):421-30.
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  148. Owan TE, Chen HH, Frantz RP, Karon BL, Miller WL, Rodeheffer RJ, Hodge DO, Burnett JC Jr, Redfield MM. The effects of nesiritide on renal function and diuretic responsiveness in acutely decompensated heart failure patients with renal dysfunction. J Card Fail. 2008 May; 14 (4):267-75
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  149. Raichlin E, McConnell JP, Bae JH, Kremers WK, Lerman A, Frantz RP. Lipoprotein-associated phospholipase A2 predicts progression of cardiac allograft vasculopathy and increased risk of cardiovascular events in heart transplant patients. Transplantation. 2008 Apr 15; 85 (7):963-8
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  150. Frantz RP. Pulmonary Arterial Hypertension - Future Directions. US Respiratory Disease. 2008; 4(2):112-114.
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  153. Raichlin E, Khalpey Z, Kremers W, Frantz RP, Rodeheffer RJ, Clavell AL, Edwards BS, Kushwaha SS. Replacement of calcineurin-inhibitors with sirolimus as primary immunosuppression in stable cardiac transplant recipients. Transplantation. 2007 Aug 27; 84(4):467-74.
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  154. Frantz RP, Lowes BD, Grayburn PA, White M, Krause-Steinrauf H, Krishnan V, Uyeda L, Burnett JC, BEST Neurohumoral Substudy Investigators. Baseline and serial neurohormones in patients with congestive heart failure treated with and without bucindolol: results of the neurohumoral substudy of the Beta-Blocker Evaluation of Survival Study (BEST). J Card Fail. 2007 Aug; 13 (6):437-44
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  156. Karamanoglu M, McGoon M, Frantz RP, Benza RL, Bourge RC, Barst RJ, Kjellstrom B, Bennett TD. Right ventricular pressure waveform and wave reflection analysis in patients with pulmonary arterial hypertension. Chest. 2007 Jul; 132(1):37-43. Epub 2007 May 15.
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  159. Krowka MJ, Swanson KL, Frantz RP, McGoon MD, Wiesner RH. Portopulmonary hypertension: Results from a 10-year screening algorithm. Hepatology. 2006 Dec; 44 (6):1502-10
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  161. Urheim S, Cauduro S, Frantz R, McGoon M, Belohlavek M, Green T, Miller F, Bailey K, Seward J, Tajik J, Abraham TP. Relation of tissue displacement and strain to invasively determined right ventricular stroke volume. Am J Cardiol. 2005 Oct 15; 96(8):1173-8. Epub 2005 Sep 01.
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  162. Frantz RP, Olson LJ, Grill D, Moualla SK, Nelson SM, Nobrega TP, Hanna RD, Backes RJ, Mookadam F, Heublein D, Bailey KR, Burnett JC. Carvedilol therapy is associated with a sustained decline in brain natriuretic peptide levels in patients with congestive heart failure. Am Heart J. 2005 Mar; 149 (3):541-7
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  163. Eichhorn EJ, Grayburn PA, Mayer SA, Sutton MS, Appleton C, Plehn J, Oh J, Greenberg B, DeMaria A, Frantz R, Krause-Steinrauf H. Myocardial contractile reserve by dobutamine stress echocardiography predicts improvement in ejection fraction with beta-blockade in patients with heart failure - The beta-Blocker Evaluation of Survival Trial (BEST). Circulation. 2003 Nov 11; 108(19):2336-41.
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  164. Bhatia S, Frantz RP, Severson CJ, Durst LA, McGoon MD. Immediate and long-term hemodynamic and clinical effects of sildenafil in patients with pulmonary arterial hypertension receiving vasodilator therapy. Mayo Clin Proc. 2003 Oct; 78 (10):1207-13
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  165. Simper D, Wang S, Deb A, Holmes D, McGregor C, Frantz R, Kushwaha SS, Caplice NM. Endothelial progenitor cells are decreased in blood of cardiac allograft patients with vasculopathy and endothelial cells of noncardiac origin are enriched in transplant atherosclerosis. Circulation. 2003 Jul 15; 108 (2):143-9 Epub 2003 June 30
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  166. Galie N, Hinderliter AL, Torbicki A, Fourme T, Simonneau G, Pulido T, Espinola-Zavaleta N, Rocchi G, Manes A, Frantz R, Kurzyna M, Nagueh SF, Barst R, Channick R, Dujardin K, Kronenberg A, Leconte I, Rainisio M, Rubin L. Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and Doppler measures in patients with pulmonary arterial hypertension. J Am Coll Cardiol. 2003 Apr 16; 41(8):1380-6.
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  167. Leung TC, Ballman KV, Allison TG, Wagner JA, Olson LJ, Frantz RP, Edwards BS, Dearani JA, Daly RC, McGregor CG, Rodeheffer RJ. Clinical predictors of exercise capacity 1 year after cardiac transplantation. J Heart Lung Transplant. 2003 Jan; 22 (1):16-27
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  168. Squires RW, Leung TC, Cyr NS, Allison TG, Johnson BD, Ballman KV, Wagner JA, Olson LJ, Frantz RP, Edwards BS, Kushwaha SS, Dearani JA, Daly RC, McGregor CG, Rodeheffer RJ. Partial normalization of the heart rate response to exercise after cardiac transplantation: frequency and relationship to exercise capacity. Mayo Clin Proc. 2002 Dec; 77(12):1295-300.
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  169. Frantz R, Olson L, Hanna RD, Backes RJ, Mookadam F, Heublein D, Bailey KR, Burnett JC. Effect of carvedilol on survival in severe chronic heart failure. Surv Anesthesiol. 2002; 46(4):227-8.
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  171. Kim WR, Krowka MJ, Plevak DJ, Lee J, Rettke SR, Frantz RP, Wiesner RH. Accuracy of Doppler echocardiography in the assessment of pulmonary hypertension in liver transplant candidates. Liver Transpl. 2000 Jul; 6: (4)453-8.
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  172. Handa N, McGregor CG, Daly RC, Dearani JA, Edwards BS, Frantz RP, Olson LJ, Rodeheffer RJ. Heart transplantation for radiation-associated end-stage heart failure. Transpl Int. 2000; 13 (2):162-5
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  173. Frantz RP, Heublein DM, Lunn RJ, Buck CF, Burnett JC. Hemodynamic and neurohumoral effects of inhaled nitric oxide and intravenous sodium nitroprusside in cardiac transplant candidates with pulmonary hypertension. American Heart Journal. 2000.
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  175. Frantz R. Consensus recommendations for the management of chronic heart failure on behalf of the membership of the advisory council to improve outcomes nationwide in heart failure. American Journal of Cardiology. 1999; 83(2A):1A-38A.
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  176. Frantz RP, Olson LJ. Recipient selection and management before cardiac transplantation. Am J Med Sci. 1997 Sep; 314 (3):139-52
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  177. Frantz RP, Edwards BS, Olson LJ, Schwab MK, Adams TF, Textor SC, Daly RC, McGregor CG, Rodeheffer RJ. Effects of pentoxifylline on renal function and blood pressure in cardiac transplant recipients: a randomized trial. Transplantation. 1997 Jun 15; 63 (11):1607-10
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  178. Chau EM, Bailey KR, Mahoney DW, Frantz RP, McGregor CG, Daly RC, Edwards BS, Olson LJ, Rodeheffer RJ. Predictors of reversibility of pulmonary hypertension in cardiac transplant recipients in the first postoperative year. Circulation. 1996 Nov 1; 94(9 Suppl):II267-72.
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  179. Chau EM, McGregor CG, Rodeheffer RJ, Frantz RP, Olson LJ, Daly RC, Edwards BS. Increased incidence of chronotropic incompetence in older donor hearts. J Heart Lung Transplant. 1995 Jul-Aug; 14(4):743-8.
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  180. Berger PB, Jones JD, Olson LJ, Edwards BS, Frantz RP, Rodeheffer RJ, Kottke BA, Daly RC, McGregor CG. Increase in total plasma homocysteine concentration after cardiac transplantation. Mayo Clin Proc. 1995 Feb; 70(2):125-31.
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  181. Frantz RP, Lerman A, Edwards BS, Olson LJ, Higano ST, Schwartz RS, Daly RC, McGregor CG, Rodeheffer RJ. Methylergonovine-induced diffuse coronary spasm in a patient with exercise-induced coronary spasm after heart transplantation. J Heart Lung Transplant. 1994 Sep-Oct; 13: (5)834-9.
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  182. Fan THM, Frantz RP, Elam H, Sakamoto S, Imai N, Liang CS. Reductions of myocardial na-k-ATPase activity and ouabain binding sites in heart failure: prevention by nadolol. Am J Physiol. 1993; (265):H2086-H2093.
  183. McGoon MD, Frantz RP. Techniques of immunosuppression after cardiac transplantation. Mayo Clin Proc. 1992 Jun; 67 (6):586-95
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  184. Liang CS, Frantz RP, Suematsu M, Sakamoto S, Sullebarger JT, Fan TM, Guthinger L. Chronic beta-adrenoceptor blockade prevents the development of beta-adrenergic subsensitivity in experimental right-sided congestive heart failure in dogs. Circulation. 1991 Jul; 84(1):254-66.
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  185. Zachariah PK, Moyer TP, Theobald HM, Frantz RP, Kurtz SB, McCarthy JT, Smith RL. The pharmacokinetics of racemic verapamil in patients with impaired renal function. J Clin Pharmacol. 1991 Jan; 31 (1):45-53
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