Xiangzhi Zhou, Ph.D.

  1. Medical Physicist
  1. Straub S, Zhou X, Tao S, Westerhold EM, Jin J, Middlebrooks EH. Feasibility of submillimeter functional quantitative susceptibility mapping using 3D echo planar imaging at 7 T. NMR Biomed. 2024 Oct 14; e5263 [Epub ahead of print]
    View PubMed
  2. Patel V, Tao S, Zhou X, Lin C, Westerhold E, Grewal S, Middlebrooks EH. Real-Time Optimal Synthetic Inversion Recovery Image Selection (RT-OSIRIS) for Deep Brain Stimulation Targeting. J Imaging Inform Med. 2024 Oct; 37 (5):2698-2705 Epub 2024 Apr 19
    View PubMed
  3. Middlebrooks EH, Patel V, Zhou X, Straub S, Murray JV Jr, Agarwal AK, Okromelidze L, Singh RB, Lopez Chiriboga AS, Westerhold EM, Gupta V, Sandhu SJS, Marin Collazo IV, Tao S. 7 T Lesion-Attenuated Magnetization-Prepared Gradient Echo Acquisition for Detection of Posterior Fossa Demyelinating Lesions in Multiple Sclerosis. Invest Radiol. 2024 Jul 1; 59 (7):513-518 Epub 2024 Jan 09
    View PubMed
  4. Middlebrooks EH, Tipton PW, Greco E, Okromelidze L, Patel V, Wszolek ZK, Zhou X, Tao S, Westerhold EM, Straub S, Uitti RJ, Sandhu SJS, Quinones-Hinojosa A, Grewal SS. Enhancing outcomes in deep brain stimulation: a comparative study of direct targeting using 7T versus 3T MRI. J Neurosurg. 2024 Jul 1; 141 (1):252-259 Epub 2024 Feb 23
    View PubMed
  5. Lakhani DA, Zhou X, Tao S, Patel V, Wen S, Okromelidze L, Greco E, Lin C, Westerhold EM, Straub S, Wszolek ZK, Tipton PW, Uitti RJ, Grewal SS, Middlebrooks EH. Diagnostic utility of 7T neuromelanin imaging of the substantia nigra in Parkinson's disease. NPJ Parkinsons Dis. 2024 Jan 08; 10(1):13.
    View PubMed
  6. Okromelidze L, Patel V, Singh RB, Lopez Chiriboga AS, Tao S, Zhou X, Straub S, Westerhold EM, Gupta V, Agarwal AK, Murray JV, Desai A, Sandhu SJS, Marin Collazo IV, Middlebrooks EH. Central Vein Sign in Multiple Sclerosis: A Comparison Study of the Diagnostic Performance of 3T versus 7T MRI. AJNR Am J Neuroradiol. 2023 Dec 29; 45 (1):76-81
    View PubMed
  7. Tao S, Zhou X, Lin C, Patel V, Westerhold EM, Middlebrooks EH. Optimization of MP2RAGE T1 mapping with radial view-ordering for deep brain stimulation targeting at 7 T MRI. Magn Reson Imaging. 2023 Jul; 100:55-63. Epub 2023 Mar 15.
    View PubMed
  8. Lakhani DA, Zhou X, Tao S, Westerhold EM, Eidelman BH, Singh Sandhu SJ, Middlebrooks EH. Clinical application of ultra-high resolution compressed sensing time-of-flight MR angiography at 7T to detect small vessel pathology. Neuroradiol J. 2023 Jun; 36 (3):335-340 Epub 2022 Sept 29
    View PubMed
  9. Lakhani DA, Zhou X, Tao S, Westerhold EM, Eidelman BH, Vibhute P, Singh Sandhu SJ, Middlebrooks EH. 7T MRI in transient ischemic attacks: Have we only seen the tip of the iceberg? Neuroradiol J. 2023 Mar 27; 19714009231166089 [Epub ahead of print]
    View PubMed
  10. Middlebrooks EH, Tao S, Zhou X, Greco E, Westerhold EM, Tipton PW, Quinones-Hinojosa A, Grewal SS, Patel V. Synthetic Inversion Image Generation using MP2RAGE T1 Mapping for Surgical Targeting in Deep Brain Stimulation and Lesioning. Stereotact Funct Neurosurg 2023; 101 (5):326-331 Epub 2023 Aug 22
    View PubMed
  11. Tao S, Zhou X, Westerhold EM, Middlebrooks EH, Lin C. Optimization of fast gray matter acquisition T1 inversion recovery (FGATIR) on 7T MRI for deep brain stimulation targeting. Neuroimage. 2022 May 15; 252:119043 Epub 2022 Feb 27
    View PubMed
  12. Watts R, Steinklein JM, Waldman L, Zhou X, Filippi CG. Measuring Glymphatic Flow in Man Using Quantitative Contrast-Enhanced MRI. AJNR Am J Neuroradiol. 2019 Apr; 40 (4):648-651 Epub 2019 Jan 24
    View PubMed
  13. Viviano JD, Buchanan RW, Calarco N, Gold JM, Foussias G, Bhagwat N, Stefanik L, Hawco C, DeRosse P, Argyelan M, Turner J, Chavez S, Kochunov P, Kingsley P, Zhou X, Malhotra AK, Voineskos AN, Social Processes Initiative in Neurobiology of the Schizophrenia(s) Group. Resting-State Connectivity Biomarkers of Cognitive Performance and Social Function in Individuals With Schizophrenia Spectrum Disorder and Healthy Control Subjects. Biol Psychiatry. 2018 Nov 1; 84 (9):665-674 Epub 2018 Apr 13
    View PubMed
  14. Miyazaki M, Zhou X, Hoshino T, Yokoyama K, Ishimura R, Nitatori T. Non-contrast myocardial perfusion using a novel 4D magnetic resonance arterial spin labeling technique: initial experience. Microvasc Res. 2015 Mar; 98:94-101 Epub 2015 Jan 30
    View PubMed
  15. Miyazaki M, Ouyang C, Zhou X, Murdoch JB, Fushimi Y, Okada T, Fujimoto K, Kido A, Arakawa Y, Miyamoto S, Togashi K. Z-Spectrum analysis provides proton environment data (ZAPPED): a new two-pool technique for human gray and white matter. PLoS One. 2015; 10 (3):e0119915 Epub 2015 Mar 13
    View PubMed
  16. Okuchi S, Okada T, Fujimoto K, Fushimi Y, Kido A, Yamamoto A, Kanagaki M, Dodo T, Mehemed TM, Miyazaki M, Zhou X, Togashi K. Visualization of lenticulostriate arteries at 3T: Optimization of slice-selective off-resonance sinc pulse-prepared TOF-MRA and its comparison with flow-sensitive black-blood MRA. Acad Radiol. 2014 Jun; 21 (6):812-6
    View PubMed
  17. Tsaftaris SA, Zhou X, Tang R, Li D, Dharmakumar R. Detecting myocardial ischemia at rest with cardiac phase-resolved blood oxygen level-dependent cardiovascular magnetic resonance. Circ Cardiovasc Imaging. 2013 Mar 1; 6 (2):311-9 Epub 2012 Dec 18
    View PubMed
  18. Kohnke T, Gomolka B, Bilal S, Zhou X, Sun Y, Rothe M, Baumgart DC, Weylandt KH. Acetylsalicylic Acid reduces the severity of dextran sodium sulfate-induced colitis and increases the formation of anti-inflammatory lipid mediators. Biomed Res Int. 2013; 2013:748160 Epub 2013 Sept 08
    View PubMed
  19. Tsaftaris SA, Tang R, Zhou X, Li D, Dharmakumar R. Ischemic extent as a biomarker for characterizing severity of coronary artery stenosis with blood oxygen-sensitive MRI. J Magn Reson Imaging. 2012 Jun; 35 (6):1338-48 Epub 2012 Jan 13
    View PubMed
  20. Zhou X, Rundell V, Liu Y, Tang R, Shah S, Zuehlsdorff S, Li D, Dharmakumar R. On the mechanisms enabling myocardial edema contrast in bSSFP-based imaging approaches. Magn Reson Med. 2011 Jul; 66 (1):187-91 Epub 2011 Mar 09
    View PubMed
  21. Zhou X, Rundell V, Liu Y, Tang R, Klein R, Shah S, Zuehlsdorff S, Tsaftaris SA, Li D, Dharmakumar R. T(2) -weighted STIR imaging of myocardial edema associated with ischemia-reperfusion injury: the influence of proton density effect on image contrast. J Magn Reson Imaging. 2011 Apr; 33 (4):962-7
    View PubMed
  22. Fan Z, Zhou X, Bi X, Dharmakumar R, Carr JC, Li D. Determination of the optimal first-order gradient moment for flow-sensitive dephasing magnetization-prepared 3D noncontrast MR angiography. Magn Reson Med. 2011 Apr; 65 (4):964-72 Epub 2011 Feb 24
    View PubMed
  23. Zhang Z, Li J, Wu S, Liu Y, Zhou X, Fan Z, Li D, Huan Y. Magnetic resonance imaging/magnetic resonance spectroscopy biomarkers evaluation of stunned myocardium in canine model. Invest Radiol. 2011 Apr; 46 (4):209-14
    View PubMed
  24. Zhang Z, Li J, Wu S, Liu Y, Fan Z, Zhou X, Zhao H, Li D, Huan Y. Cine-MRI and (31)P-MRS for evaluation of myocardial energy metabolism and function following coronary artery bypass graft. Magn Reson Imaging. 2010 Sep; 28 (7):936-42 Epub 2010 May 04
    View PubMed
  25. Zhou X, Tsaftaris SA, Liu Y, Tang R, Klein R, Zuehlsdorff S, Li D, Dharmakumar R. Artifact-reduced two-dimensional cine steady state free precession for myocardial blood- oxygen-level-dependent imaging. J Magn Reson Imaging. 2010 Apr; 31 (4):863-71
    View PubMed
  26. Zhou X, Tang R, Klein R, Li D, Dharmakumar R. Parametric dependence of myocardial blood oxygen level dependent, balanced steady-state free-precession imaging at 1.5 T: theory and experiments. Magn Reson Med. 2010 Feb; 63 (2):484-93
    View PubMed
  27. Zhou X, Bao H, Takakura A, Zhou J, Albert M, Sun Y. Polycystic kidney disease evaluation by magnetic resonance imaging in ischemia-reperfusion injured PKD1 knockout mouse model: comparison of T2-weighted FSE and true-FISP. Invest Radiol. 2010 Jan; 45 (1):24-8
    View PubMed
  28. Takakura A, Contrino L, Zhou X, Bonventre JV, Sun Y, Humphreys BD, Zhou J. Renal injury is a third hit promoting rapid development of adult polycystic kidney disease. Hum Mol Genet. 2009 Jul 15; 18 (14):2523-31 Epub 2009 Apr 02
    View PubMed
  29. Zhou X, Bao H, Al-Hashem R, Ji H, Albert M, Wong KK, Sun Y. Magnetic resonance imaging of the response of a mouse model of non-small cell lung cancer to tyrosine kinase inhibitor treatment. Comp Med. 2008 Jun; 58 (3):276-81
    View PubMed
  30. Zhou X, Westlund PO. The viscosity and temperature dependence of X-band ESR lineshapes of Gd(III) aqueous complex. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Nov; 62 (1-3):76-82 Epub 2005 Jan 22
    View PubMed
  31. Zhou X, Westlund PO. The viscosity and temperature dependence of (1)H T(1)-NMRD of the Gd(H(2)O)(8)(3+) complex. Spectrochim Acta A Mol Biomol Spectrosc. 2005 Nov; 62 (1-3):335-42
    View PubMed
  32. Zhou X, Westlund PO. 1H NMRD profiles and ESR lineshapes of Gd(III) complexes: a comparison between the generalized SBM and the stochastic Liouville approach. J Magn Reson. 2005 Mar; 173 (1):75-83
    View PubMed
  33. Zhou X, Caravan P, Clarkson RB, Westlund PO. On the philosophy of optimizing contrast agents. An analysis of 1H NMRD profiles and ESR lineshapes of the Gd(III)complex MS-325+HSA. J Magn Reson. 2004 Mar; 167 (1):147-60
    View PubMed