Lori R. Roust, M.D.
Endocrinologist
Internist
Freitas EDS, Kras KA,
Roust LR
, De Filippis EA, Kimball SR, Buras M, Katsanos CS. Lower muscle protein synthesis in humans with obesity concurrent with lower expression of muscle IGF1 splice variants. Obesity (Silver Spring). 2023 Nov; 31 (11):2689-2698 Epub 2023 Oct 16
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Garcia LA, Zapata-Bustos R, Day SE, Campos B, Hamzaoui Y, Wu L, Leon AD, Krentzel J, Coletta RL, De Filippis E,
Roust LR
, Mandarino LJ, Coletta DK. Can Exercise Training Alter Human Skeletal Muscle DNA Methylation? Metabolites. 2022 Mar 2; 12 (3) Epub 2022 Mar 02
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Ravichandran J,
Roust LR
, Katsanos CS. Increased Expression of Syncytin-1 in Skeletal Muscle of Humans With Increased Body Mass Index. Front Physiol. 2022; 13:858341 Epub 2022 Apr 04
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Garcia LA, Day SE, Coletta RL, Campos B, Benjamin TR, De Filippis E, Madura JA 2nd, Mandarino LJ,
Roust LR
, Coletta DK. Weight loss after Roux-En-Y gastric bypass surgery reveals skeletal muscle DNA methylation changes. Clin Epigenetics. 2021 May 1; 13 (1):100 Epub 2021 May 01
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Serrano N, Tran L, Hoffman N,
Roust L
, De Filippis EA, Carroll CC, Patel SH, Kras KA, Buras M, Katsanos CS. Lack of Increase in Muscle Mitochondrial Protein Synthesis During the Course of Aerobic Exercise and Its Recovery in the Fasting State Irrespective of Obesity. Front Physiol. 2021; 12:702742 Epub 2021 Aug 02
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Patel NJ, Gomez V, Steidley DE,
Roust L
, Leoni Moreno JC, Abraham NS, Pannala R. Successful Use of Intragastric Balloon Therapy as a Bridge to Heart Transplantation. Obes Surg. 2020 Sep; 30 (9):3610-3614
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Wahwah N, Kras KA,
Roust LR
, Katsanos CS. Subpopulation-specific differences in skeletal muscle mitochondria in humans with obesity: insights from studies employing acute nutritional and exercise stimuli. Am J Physiol Endocrinol Metab. 2020 Apr 1; 318 (4):E538-E553 Epub 2020 Jan 28
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Kras KA, Hoffman N,
Roust LR
, Benjamin TR, DE Filippis EA, Katsanos CS. Adenosine Triphosphate Production of Muscle Mitochondria after Acute Exercise in Lean and Obese Humans. Med Sci Sports Exerc. 2019 Mar; 51 (3):445-453
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Tran L, Langlais PR, Hoffman N,
Roust L
, Katsanos CS. Mitochondrial ATP synthase beta-subunit production rate and ATP synthase specific activity are reduced in skeletal muscle of humans with obesity. Exp Physiol. 2019 Jan; 104 (1):126-135 Epub 2018 Nov 12
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Kras KA, Langlais PR, Hoffman N,
Roust LR
, Benjamin TR, De Filippis EA, Dinu V, Katsanos CS. Obesity modifies the stoichiometry of mitochondrial proteins in a way that is distinct to the subcellular localization of the mitochondria in skeletal muscle. Metabolism. 2018 Dec; 89:18-26 Epub 2018 Sept 22
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Tran L, Kras KA, Hoffman N, Ravichandran J, Dickinson JM, D'Lugos A, Carroll CC, Patel SH, Mandarino LJ,
Roust L
, Katsanos CS. Lower Fasted-State but Greater Increase in Muscle Protein Synthesis in Response to Elevated Plasma Amino Acids in Obesity. Obesity (Silver Spring). 2018 Jul; 26 (7):1179-1187 Epub 2018 June 12
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Kras KA, Hoffman N,
Roust LR
, Patel SH, Carroll CC, Katsanos CS. Plasma Amino Acids Stimulate Uncoupled Respiration of Muscle Subsarcolemmal Mitochondria in Lean but Not Obese Humans. J Clin Endocrinol Metab. 2017 Dec 1; 102 (12):4515-4525
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Day SE, Coletta RL, Kim JY, Garcia LA, Campbell LE, Benjamin TR,
Roust LR
, De Filippis EA, Mandarino LJ, Coletta DK. Potential epigenetic biomarkers of obesity-related insulin resistance in human whole-blood. Epigenetics. 2017 Apr 3; 12 (4):254-263 Epub 2017 Jan 20
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Roust LR
, DiBaise JK. Nutrient deficiencies prior to bariatric surgery. Curr Opin Clin Nutr Metab Care. 2017 Mar; 20 (2):138-144
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Day SE, Garcia LA, Coletta RL, Campbell LE, Benjamin TR, De Filippis EA, Madura JA 2nd, Mandarino LJ,
Roust LR
, Coletta DK. Alterations of sorbin and SH3 domain containing 3 (SORBS3) in human skeletal muscle following Roux-en-Y gastric bypass surgery. Clin Epigenetics. 2017; 9:96 Epub 2017 Sept 02
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Campbell LE, Langlais PR, Day SE, Coletta RL, Benjamin TR, De Filippis EA, Madura JA 2nd, Mandarino LJ,
Roust LR
, Coletta DK. Identification of Novel Changes in Human Skeletal Muscle Proteome After Roux-en-Y Gastric Bypass Surgery. Diabetes. 2016 Sep; 65 (9):2724-31 Epub 2016 May 10
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Tran L, Hanavan PD, Campbell LE, De Filippis E, Lake DF, Coletta DK,
Roust LR
, Mandarino LJ, Carroll CC, Katsanos CS. Prolonged Exposure of Primary Human Muscle Cells to Plasma Fatty Acids Associated with Obese Phenotype Induces Persistent Suppression of Muscle Mitochondrial ATP Synthase beta Subunit. PLoS One. 2016; 11 (8):e0160057 Epub 2016 Aug 17
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Day SE, Coletta RL, Kim JY, Campbell LE, Benjamin TR,
Roust LR
, De Filippis EA, Dinu V, Shaibi GQ, Mandarino LJ, Coletta DK. Next-generation sequencing methylation profiling of subjects with obesity identifies novel gene changes. Clin Epigenetics. 2016; 8:77 Epub 2016 July 18
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Katsanos CS, Madura JA 2nd,
Roust LR
. Essential amino acid ingestion as an efficient nutritional strategy for the preservation of muscle mass following gastric bypass surgery. Nutrition. 2016 Jan; 32 (1):9-13 Epub 2015 Aug 05
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Tran L, Masters H,
Roust LR
, Katsanos CS. A new method to measure muscle protein synthesis in humans by endogenously introduced d9-leucine and using blood for precursor enrichment determination. Physiol Rep. 2015 Aug; 3 (8)
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Swanson CM,
Roust LR
, Miller K, Madura JA 2nd. What every hospitalist should know about the post-bariatric surgery patient. J Hosp Med. 2012 Feb; 7(2):156-63. Epub 2011 Nov 15.
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Whited MH,
Roust LR
, Bersoux S, Mayer AP, Files JA, Blair JE, Ko MG. Medical management of obesity. Current Nutrition and Food Science. 2008; 4(2):145-53.
Cook CB, Castro JC, Schmidt RE, Gauthier SM, Whitaker MD,
Roust LR
, Argueta R, Hull BP, Zimmerman RS. Diabetes care in hospitalized noncritically ill patients: More evidence for clinical inertia and negative therapeutic momentum. J Hosp Med. 2007 Jul; 2(4):203-11.
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Cook CB, McNaughton DA, Braddy CM, Jameson KA,
Roust LR
, Smith SA, Roberts DL, Thomas SL, Hull BP. Management of inpatient hyperglycemia: assessing perceptions and barriers to care among resident physicians. Endocr Pract. 2007 Mar-Apr; 13 (2):117-24
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Santelli AC, Blair JE,
Roust LR
. Coccidioidomycosis in patients with diabetes mellitus. Am J Med. 2006 Nov; 119(11):964-9.
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Cook CB, Boyle ME, Cisar NS, Miller-Cage V, Bourgeois P,
Roust LR
, Smith SA, Zimmerman RS. Use of continuous subcutaneous insulin infusion (insulin pump) therapy in the hospital setting: proposed guidelines and outcome measures. Diabetes Educ. 2005 Nov-Dec; 31 (6):849-57
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Collins R, Schlinkert RT,
Roust L
. Laparoscopic resection of an insulinoma. J Laparoendosc Adv Surg Tech A. 1999 Oct; 9(5):429-31.
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Roust LR
, Kottke BA, Jensen MD. Serum lipid responses to a eucaloric high-complex carbohydrate diet in different obesity phenotypes. Mayo Clin Proc. 1994 Oct; 69 (10):930-6
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Roust LR
, Hammel KD, Jensen MD. Effects of isoenergetic, low-fat diets on energy metabolism in lean and obese women. Am J Clin Nutr. 1994 Oct; 60 (4):470-5
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Jensen MD, Martin ML, Cryer PE,
Roust LR
. Effects of estrogen on free fatty acid metabolism in humans. Am J Physiol. 1994 Jun; 266 (6 Pt 1):E914-20
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Roust LR
, Jensen MD. Postprandial free fatty acid kinetics are abnormal in upper body obesity. Diabetes. 1993 Nov; 42 (11):1567-73
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Jensen MD, Kanaley JA,
Roust LR
, O'Brien PC, Braun JS, Dunn WL, Wahner HW. Assessment of body composition with use of dual-energy x-ray absorptiometry: evaluation and comparison with other methods. Mayo Clin Proc. 1993 Sep; 68 (9):867-73
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Roust LR
, Stesin M, Go VL, O'Brien PC, Rizza RA, Service FJ. Role of gastric inhibitory polypeptide in postprandial hyperinsulinemia of obesity. Am J Physiol. 1988 Jun; 254 (6 Pt 1):E767-74
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