Mohamed Elrefaei, M.D., Ph.D.

  1. Immunogeneticist
  2. Laboratory Immunologist
  1. Narula T, Alvarez F, Abdelmoneim Y, Erasmus D, Li Z, Elrefaei M. Induction immunosuppression strategies and outcomes post-lung transplant: A single center experience. Transpl Immunol. 2024 Aug; 85:102081 Epub 2024 July 08
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  2. Brow D, Shike H, Kendrick J, Pettersson L, Mineishi S, Claxton DF, Wirk B, Cioccio J, Greiner RJ, Viswanatha D, Kharfan-Dabaja MA, Li Z, Tyler J, Elrefaei M. Assessment of chimerism by next generation sequencing: A comparison to STR/qPCR methods. Hum Immunol. 2024 May; 85 (3):110794 Epub 2024 Mar 28
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  3. Xu Q, Elrefaei M, Taupin JL, Hitchman KMK, Hiho S, Gareau AJ, Iasella CJ, Marrari M, Belousova N, Bettinotti M, Narula T, Alvarez F, Sanchez PG, Levvey B, Westall G, Snell G, Levine DJ, Zeevi A, Roux A. Chronic lung allograft dysfunction is associated with an increased number of non-HLA antibodies. J Heart Lung Transplant. 2024 Apr; 43 (4):663-672 Epub 2023 Dec 21
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  4. Du Z, Murrin ME, Patel PB, Williams CD, Elrefaei M. Identification of the novel HLA-DQA1*05:101 allele by next-generation sequencing in a family. HLA. 2024 Mar; 103 (3):e15443
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  5. Du Z, Williams C, Robinson T, Hardage B, Elrefaei M. Identification of the novel HLA-C*03:648 allele by next generation sequencing. HLA. 2024 Jan; 103 (1):e15324 Epub 2023 Dec 11
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  6. Du Z, Williams C, Santiago R, Ussery T, Elrefaei M. Identification of the novel HLA-B*57:168 allele by next generation sequencing. HLA. 2024 Jan; 103 (1):e15327 Epub 2023 Dec 11
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  7. Hanouneh T, Attieh RM, Craver E, Jebrini A, Elrefaei M, Jarmi T. Comparative analysis of Basiliximab and Alemtuzumab induction therapies in blood type A2-to-B kidney transplantation: Impact on kidney function and de novo donor-specific HLA antibodies. Transpl Immunol. 2023 Dec; 81:101958. Epub 2023 Nov 09.
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  8. Ibrahim IH, Ali OSM, El-Sahar AA, Elrefaei M, El-Sheikh N. Telomerase Expression Related with Poor Immune Response to HCV Core Antigen in Egyptian HCV Patients' PBMCs. J Clin Exp Hepatol. 2023 Nov-Dec; 13 (6):1008-1016 Epub 2023 June 19
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  9. Jarmi T, Abdelmoneim Y, Li Z, Jebrini A, Elrefaei M. Basiliximab is associated with a lower incidence of De novo donor-specific HLA antibodies in kidney transplant recipients: A single-center experience. Transpl Immunol. 2023 Apr; 77:101778 Epub 2022 Dec 28
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  10. Shah SZ, Abdelmoneim Y, Pham SM, Elrefaei M. Association between SARS-CoV-2 infection and de novo HLA donor specific antibody production in lung transplant recipients: Single-center study. Hum Immunol. 2022 Nov; 83 (11):749-754 Epub 2022 Aug 15
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  11. Pereira ROL, Rodrigues ES, Martin AK, Narula T, Ball CT, Alvarez F, Erasmus DB, Elrefaei M, Pham SM, Salinas JLZ, Thomas M. Outcomes After Lung Retransplantation: A Single-Center Retrospective Cohort Study. J Cardiothorac Vasc Anesth. 2022 May; 36 (5):1366-1372 Epub 2021 Aug 22
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  12. Powers HR, Hellinger WC, Cortese C, Elrefaei M, Khouzam S, Spiegel M, Li Z, Wadei HM. Histologic acute graft pyelonephritis after kidney transplantation: Incidence, clinical characteristics, risk factors, and association with graft loss. Transpl Infect Dis. 2022 Apr; 24 (2):e13801 Epub 2022 Feb 07
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  13. Narula T, Khouzam S, Alvarez F, Erasmus D, Li Z, Abdelmoneim Y, Elrefaei M. Antithymocyte globulin is associated with a lower incidence of de novo donor-specific antibody detection in lung transplant recipients: A single-center experience. Immun Inflamm Dis. 2021 Dec; 9 (4):1418-1427 Epub 2021 July 26
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  14. El-Sheikh N, Mousa NO, Osman A, Tawfeik AM, Taha BA, Mahran H, Saleh AM, El-Shiekh I, Amin W, Elrefaei M. Assessment of Interferon Gamma-Induced Protein 10 mRNA Release Assay for Detection of Latent Tuberculosis Infection in Egyptian Pediatric Household Contacts. Int J Infect Dis. 2021 Aug; 109:223-229 Epub 2021 July 13
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  15. El-Sheikh N, Mousa NO, Tawfeik AM, Saleh AM, Elshikh I, Deyab M, Ragheb F, Moneer MM, Kawashti A, Osman A, Elrefaei M. Assessment of Human Papillomavirus Infection and Risk Factors in Egyptian Women With Breast Cancer. Breast Cancer (Auckl). 2021; 15:1178223421996279 Epub 2021 Feb 25
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  16. Khouzam S, Narula T, Alvarez F, Elrefaei M. Antithymocyte Globulin is Associated with a Lower Incidence of De Novo Donor-Specific Antibody Detection in Lung Transplant Recipients: A Single-Center Experience. J Heart Lung Transplant. 2020 Apr; 39 (4S):S324 Epub 2020 Mar 30
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  17. Tawfeik AM, Mora A, Osman A, Moneer MM, El-Sheikh N, Elrefaei M. Frequency of CD4+ regulatory T cells, CD8+ T cells, and human papilloma virus infection in Egyptian Women with breast cancer. Int J Immunopathol Pharmacol. 2020 Jan-Dec; 34:2058738420966822
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  18. Khoor A, Roden AC, Colby TV, Roggli VL, Elrefaei M, Alvarez F, Erasmus DB, Mallea JM, Murray DL, Keller CA. Giant cell interstitial pneumonia in patients without hard metal exposure: analysis of 3 cases and review of the literature. Hum Pathol. 2016 Apr; 50:176-82 Epub 2015 Dec 18
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  19. Elrefaei M, Boose K, McGee M, Tarrant TK, Lin FC, Fine JP, Schmitz JL. Second generation automated anti-CCP test better predicts the clinical diagnosis of rheumatoid arthritis. J Clin Immunol. 2012 Feb; 32(1):131-7. Epub 2011 Nov 10.
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  20. Elrefaei M, Burke CM, Baker CA, Jones NG, Bousheri S, Bangsberg DR, Cao H. HIV-specific TGF-beta-positive CD4+ T cells do not express regulatory surface markers and are regulated by CTLA-4. AIDS Res Hum Retroviruses. 2010 Mar; 26(3):329-37.
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  21. Elrefaei M, Burke CM, Baker CA, Jones NG, Bousheri S, Bangsberg DR, Cao H. TGF-beta and IL-10 production by HIV-specific CD8+ T cells is regulated by CTLA-4 signaling on CD4+ T cells. PLoS One. 2009; 4(12):e8194. Epub 2009 Dec 14.
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  22. Elrefaei M, Baker CA, Jones NG, Bangsberg DR, Cao H. Presence of suppressor HIV-specific CD8+ T cells is associated with increased PD-1 expression on effector CD8+ T cells. J Immunol. 2008 Jun 1; 180(11):7757-63.
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  23. Ssewanyana I, Elrefaei M, Dorsey G, Ruel T, Jones NG, Gasasira A, Kamya M, Nakiwala J, Achan J, Charlebois E, Havlir D, Cao H. Profile of T cell immune responses in HIV-infected children from Uganda. J Infect Dis. 2007 Dec 1; 196(11):1667-70. Epub 2007 Oct 25.
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  24. Baker CA, Emenyonu N, Ssewanyana I, Jones NG, Elrefaei M, Nghania F, Nakiwala J, Andia I, Clark R, Martin J, Bangsberg DR, Cao H. Profile of immunologic recovery in HIV-infected Ugandan adults after antiretroviral therapy. AIDS Res Hum Retroviruses. 2007 Jul; 23(7):900-5.
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  25. Elrefaei M, Ventura FL, Baker CA, Clark R, Bangsberg DR, Cao H. HIV-specific IL-10-positive CD8+ T cells suppress cytolysis and IL-2 production by CD8+ T cells. J Immunol. 2007 Mar 1; 178(5):3265-71.
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  26. Elrefaei M, Barugahare B, Ssali F, Mugyenyi P, Cao H. HIV-specific IL-10-positive CD8+ T cells are increased in advanced disease and are associated with decreased HIV-specific cytolysis. J Immunol. 2006 Jan 15; 176(2):1274-80.
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  27. McEvers K, Elrefaei M, Norris P, Deeks S, Martin J, Lu H, Cao H. Use of modified fusion proteins for antigen delivery by MHC Class I or II in T cell assays. Vaccine. 14 July 2005; 23(32):4128-4135. Epub 2005 Apr 15
  28. McElroy MD, Elrefaei M, Jones N, Ssali F, Mugyenyi P, Barugahare B, Cao H. Coinfection with Schistosoma mansoni is associated with decreased HIV-specific cytolysis and increased IL-10 production. J Immunol. 2005 Apr 15; 174(8):5119-23.
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  29. Barugahare B, Baker C, K'Aluoch O, Donovan R, Elrefaei M, Eggena M, Jones N, Mutalya S, Kityo C, Mugyenyi P, Cao H. Human immunodeficiency virus-specific responses in adult Ugandans: patterns of cross-clade recognition. J Virol. 2005 Apr; 79(7):4132-9.
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  30. Elrefaei M, McElroy MD, Preas CP, Hoh R, Deeks S, Martin J, Cao H. Central memory CD4+ T cell responses in chronic HIV infection are not restored by antiretroviral therapy. J Immunol. 2004 Aug 1; 173(3):2184-9.
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  31. Elrefaei M, El-sheikh N, Kamal K, Cao H. Analysis of T cell responses against hepatitis C virus genotype 4 in Egypt. J Hepatol. 2004 Feb; 40(2):313-8.
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  32. Elrefaei M, El-Sheikh N, Kamal K, Cao H. HCV-specific CD27- CD28- memory T cells are depleted in hepatitis C virus and Schistosoma mansoni co-infection. Immunology. 2003 Dec; 110(4):513-8.
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  33. Jones N, Agrawal D, Elrefaei M, Hanson A, Novitsky V, Wong JT, Cao H. Evaluation of antigen-specific responses using in vitro enriched T cells. J Immunol Methods. 2003 Mar 1; 274(1-2):139-47.
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  34. Elrefaei M, Blank KJ, Murasko DM. Decreased IL-2, IFN-gamma, and IL-10 production by aged mice during the acute phase of E55+ retrovirus infection. Virology. 2002 Jul 20; 299(1):8-19.
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  35. Elrefaei M, Blank KJ, Murasko DM. Prolonged E55+ retrovirus expression in aged mice is associated with a decline in the anti-virus immune response. Virology. 2001 Nov 25; 290(2):281-9.
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  36. Rumbely CA, Sugaya H, Zekavat SA, Elrefaei M, Perrin PJ, Phillips SM. Activated eosinophils are the major source of Th2-associated cytokines in the schistosome granuloma. J Immunol. 1999; 162:1003-1009.
  37. Afifi S, Hegazi F, Elrefaei M, Ashour MS, Elsheikh N. Detection of cytokine gene expression in schistosoma mansoni vaccine model by In situ hybridization technique. Egyptian J Immunol. 1998; 5:187-96.
  38. Maklad S, Mobdy HR, Elrefaei M, Galal N, Phillips SM, Elsheikh N. Adhesion molecules in human schistosomiasis: I. their expression correlates with protection against schistosoma mansoni. Egyptian J Immunol. 1997; 4:373-81.