Freddy Del-Carpio Munoz, M.D.
Cardiac Electrophysiologist
Cardiologist
Del-Carpio Munoz F
, Mulpuru S, Luethe E, Carpenter C, Cagin C, Liu K, Chen J, Cha YM, Friedman P, Liu X. Impact of left bundle branch area pacing as the primary cardiac resynchronization strategy versus bi-ventricular pacing on resource utilization and clinical outcomes in a community hospital. Heart Rhythm. 2024 Jul 31 Epub 2024 July 31
View PubMed
Chen J, Ezzeddine FM, Liu X, Vaidya V, McLeod CJ, Valverde AM,
Del-Carpio Munoz F
, Deshmukh AJ, Madhavan M, Killu AM, Mulpuru SK, Friedman PA, Cha YM. Left bundle branch pacing vs ventricular septal pacing for cardiac resynchronization therapy. Heart Rhythm O2. 2024 Mar; 5 (3):150-157 Epub 2024 Jan 24
View PubMed
Chen J, Ezzeddine FM, Liu X,
Del-Carpio Munoz F
, Friedman P, Cha YM. Using artificial intelligence-enabled electrocardiogram to predict cardiac resynchronization therapy outcomes of left bundle branch area pacing. Europace. 2023 Dec 28; 26 (1)
View PubMed
Narvaez-Guerra O, Osorio B, Gentile B,
Del-Carpio Munoz F
. Electrocardiographic spiked-helmet sign in critical non-cardiac illness. BMJ Case Rep. 2023 Oct 9; 16 (10) Epub 2023 Oct 09
View PubMed
Ezzeddine FM, Haq IU, Heinrich CK, Jain V, Enger NJ, Schultz ZC, Deshmukh AJ,
Del-Carpio Munoz F
, Asirvatham SJ, Kapa S, Bowen JM. Mitral annular disjunction and arrhythmias in Marfan syndrome. Heart Rhythm. 2023 Oct; 20 (10):1461-1462 Epub 2023 July 03
View PubMed
Ezzeddine FM, Killu AM, Deshmukh AJ,
Munoz FD
. Inappropriate shocks due to P-wave oversensing in a patient with a subcutaneous implantable cardioverter-defibrillator. J Interv Card Electrophysiol. 2023 Sep 5 Epub 2023 Sept 05
View PubMed
Ezzeddine FM, Agboola KM, Hassett LC, Killu AM,
Del-Carpio Munoz F
, DeSimone CV, Kowlgi GN, Deshmukh AJ, Siontis KC. Catheter ablation of atrial fibrillation in patients with and without hypertrophic cardiomyopathy: systematic review and meta-analysis. Europace. 2023 Aug 2; 25 (9)
View PubMed
Mai W, Schwartz L, Kneeland C, Meyers-Laplace T, Brusa D, Davis M, Ryan J, Nelson C, Vaidya V, Sorajja D, Cragun K,
Del Carpio Munoz F
, Cha YM, Jhawar N, Kusumoto F. Impact of CIED Field Advisories: Unreimbursed Costs to Medical Systems. Circ Arrhythm Electrophysiol 2023 Jun; 16 (6):e011764 Epub 2023 May 31
View PubMed
Gupta AR, Deshmukh AJ,
Del-Carpio Munoz F
. A Tale of Two Parallel Rhythms. Circulation. 2023 May 9; 147 (19):1463-1466 Epub 2023 May 08
View PubMed
Khalil F, Toya T, Ahmad A, Siontis KC, Mulpuru SK,
Del-Carpio Munoz F
, Cha YM, Friedman PA, Munger T, Asirvatham SJ, Killu AM. Ventricular arrhythmias in patients with prior aortic valve intervention: Characteristics, ablation and outcomes. J Cardiovasc Electrophysiol. 2023 May; 34 (5):1206-1215 Epub 2023 Apr 06
View PubMed
Raina A, Gersh BJ, Asirvatham SJ,
Del-Carpio Munoz F
. Characterization of ventricular arrhythmias and sudden cardiac death in subjects with mitral valve prolapse and mitral annular disjunction. Heart Rhythm. 2023 Jan; 20 (1):112-121 Epub 2022 Sept 13
View PubMed
Ladejobi A, Christopoulos G, Tan N, Ladas TP, Tri J, van Zyl M, Yasin O, Sugrue A, Khabsa M, Uecker DR, Connolly RJ, Danitz DJ, DeSimone CV, Killu AM, Maor E, Holmes D, Asirvatham SJ,
Del-Carpio Munoz F
. Effects of Pulsed Electric Fields on the Coronary Arteries in Swine. Circ Arrhythm Electrophysiol. 2022 Oct; 15 (10):e010668 Epub 2022 Oct 04
View PubMed
Sugrue A, Maor E,
Del-Carpio Munoz F
, Killu AM, Asirvatham SJ. Cardiac ablation with pulsed electric fields: principles and biophysics. Europace. 2022 Sep 1; 24 (8):1213-1222
View PubMed
Ezzeddine FM, Siontis KC, Giudicessi J, Ackerman MJ, Killu AM, Deshmukh AJ, Madhavan M, van Zyl M, Vaidya VR, Karki R, Tseng A, Munger TM, McLeod CJ, Asirvatham SJ,
Del-Carpio Munoz F
. Substrate Characterization and Outcomes of Catheter Ablation of Ventricular Arrhythmias in Patients With Mitral Annular Disjunction. Circ Arrhythm Electrophysiol. 2022 Sep; 15 (9):e011088 Epub 2022 Sept 08
View PubMed
Ezzeddine FM, Ward RC, Jiang Z, Tri JA, Agboola K, Hu T, Lodhi F, Tan NY, Ladas TP, Christopoulos G, Sugrue AM, Tolkacheva EG,
Munoz FD
, McLeod CJ, Asirvatham SJ, DeSimone CV. Novel insights into the substrate involved in maintenance of ventricular fibrillation: results from continuous multipolar mapping in a canine model. J Interv Card Electrophysiol. 2022 Aug 10 [Epub ahead of print]
View PubMed
Tan NY, Ladas TP, Christopoulos G, Sugrue AM, van Zyl M, Ladejobi AO, Lodhi FK, Hu TY, Ezzeddine FM, Agboola K, Uecker D, Maor E, Tri JA, Jiang Z, Yasin OZ, DeSimone CV, Killu AM, Asirvatham SJ,
Del-Carpio Munoz F
. Ventricular nanosecond pulsed electric field delivery using active fixation leads: a proof-of-concept preclinical study. J Interv Card Electrophysiol. 2022 Jun 30 Epub 2022 June 30
View PubMed
Tapia-Orihuela RK, Gharacholou SM, Asirvatham SJ,
Munoz FD
. Electrocardiographic markers of cardiac resynchronization therapy response: delayed time to intrinsicoid deflection onset in lateral leads. J Geriatr Cardiol. 2022 Jan 28; 19 (1):21-30
View PubMed
Ola O, Gharacholou SM,
Del-Carpio Munoz F
. Massive Discordant T-Wave Alternans and Imminent Torsades de Pointes: The "Elephant in the Room". JAMA Intern Med. 2021 Oct 1; 181 (10):1393-1395
View PubMed
Tan NY, Christopoulos G, Ladas TP, Jiang Z, Sugrue AM, Tri JA, Tolkacheva EG,
Del-Carpio Munoz F
, McLeod CJ, Asirvatham SJ, DeSimone CV. Regional and Temporal Variation of Ventricular and Conduction Tissue Activity During Ventricular Fibrillation in Canines. Circ Arrhythm Electrophysiol. 2021 Oct; 14 (10):e010281 Epub 2021 Sept 27
View PubMed
Tapia-Orihuela RKA, Gutierrez OJ,
Del-Carpio Munoz F
. A "Carousel" ECG Confusion. Circulation. 2021 May 4; 143 (18):1824-1827 Epub 2021 May 03
View PubMed
Gharacholou SM,
Del-Carpio Munoz F
, Motiei A, Sandhu GS, Barsness GW, Gulati R, Wright RS, Pellikka PA, Lewis B, Johnson MP, Lane GE, Pollak PM, Pillai DP, Sabbagh AE, Paul TK, Pham SM, Singh M. Characteristics and Long-Term Outcomes of Patients With Prior Coronary Artery Bypass Grafting Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction. Am J Cardiol. 2020 Nov 15; 135:1-8. Epub 2020 Aug 28.
View PubMed
Khalil F,
Del-Carpio Munoz F
, Deshmukh A, Killu AM. Left ventricular pacing induced polymorphic ventricular tachycardia via the adaptive left ventricle pacing algorithm. Clin Case Rep. 2020 Aug; 8 (8):1511-1516 Epub 2020 May 26
View PubMed
Slotwiner DJ, Raitt MH,
Del-Carpio Munoz F
, Mulpuru SK, Nasser N, Peterson PN. Impact of physiologic pacing versus right ventricular pacing among patients with left ventricular ejection fraction greater than 35%: A systematic review for the 2018 ACC/AHA/HRS guideline on the evaluation and management of patients with bradycardia and cardiac conduction delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Heart Rhythm. 2019 Sep; 16 (9):e280-e298 Epub 2018 Nov 06
View PubMed
Slotwiner DJ, Raitt MH,
Del-Carpio Munoz F
, Mulpuru SK, Nasser N, Peterson PN. Impact of Physiologic Pacing Versus Right Ventricular Pacing Among Patients With Left Ventricular Ejection Fraction Greater Than 35%: A Systematic Review for the 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. J Am Coll Cardiol. 2019 Aug 20; 74 (7):988-1008 Epub 2018 Nov 06
View PubMed
Slotwiner DJ, Raitt MH,
Del-Carpio Munoz F
, Mulpuru SK, Nasser N, Peterson PN. Impact of Physiologic Pacing Versus Right Ventricular Pacing Among Patients With Left Ventricular Ejection Fraction Greater Than 35%: A Systematic Review for the 2018 ACC/AHA/HRS Guideline on the Evaluation and Management of Patients With Bradycardia and Cardiac Conduction Delay: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Rhythm Society. Circulation. 2019 Aug 20; 140 (8):e483-e503 Epub 2018 Nov 06
View PubMed
Aliwaiai M, Caceres-Figueroa PP,
Del-Carpio Munoz F
. A Moving Anecdote: Exercise-Induced Vasovagal Sinus Arrest. Am J Med. 2019 Apr; 132 (4):471-475 Epub 2018 Nov 30
View PubMed
Agasthi P, Lee JZ, Amin M, Al-Saffar F, Goel V, Tseng A, Almader-Douglas D, Killu AM, Deshmukh AJ,
Del-Carpio Munoz F
, Mulpuru SK. Catheter ablation for treatment of atrial fibrillation in patients with heart failure with reduced ejection fraction: A systematic review and meta-analysis. J Arrhythm. 2019 Apr; 35 (2):171-181 Epub 2019 Jan 17
View PubMed
Yang M, Li X, Yang D, Li Y, Zhou S, Liang J, Wu G,
Del-Carpio Munoz F
, Chen HH, Friedman PA, Cha YM. Cardiac resynchronization therapy improves myocardial conduction. Pacing Clin Electrophysiol. 2019 Feb; 42 (2):238-246 Epub 2018 Dec 27
View PubMed
Del-Carpio Munoz F
, Noseworthy PA, Gharacholou SM, Scott CG, Nkomo VT, Lopez-Jimenez F, Cha YM, Munger TM, Friedman PA, Asirvatham SJ. Fragmentation of QRS complex during ventricular pacing is associated with ventricular arrhythmic events in patients with left ventricular dysfunction. J Cardiovasc Electrophysiol. 2018 Sep; 29 (9):1248-1256 Epub 2018 June 20
View PubMed
Gharacholou SM, Ijioma NN, Lennon RJ, Rihal CS, Bell MR, Brenes-Salazar JA, Sandhu GS, Gulati R, Pellikka PA, Pollak PM, Lane GE, Pillai DP,
Munoz FD
, Motiei A, Singh M. Characteristics and long term outcomes of patients with acute coronary syndromes due to culprit left main coronary artery disease treated with percutaneous coronary intervention. Am Heart J. 2018 May; 199:156-162. Epub 2018 Feb 22.
View PubMed
Del-Carpio Munoz F
, Gharacholou SM, Scott CG, Nkomo VT, Lopez-Jimenez F, Cha YM, Munger TM, Friedman PA, Asirvatham SJ. Prolonged Ventricular Conduction and Repolarization During Right Ventricular Stimulation Predicts Ventricular Arrhythmias and Death in Patients With Cardiomyopathy. JACC Clin Electrophysiol. 2017 Dec 26; 3 (13):1580-1591 Epub 2017 Sept 13
View PubMed
Gharacholou SM, Ijioma N, Banwart E,
Munoz FD
. ST-Segment Elevation Myocardial Infarction and Normal Coronary Arteries after Consuming Energy Drinks. Case Rep Cardiol. 2017; 2017:4061205 Epub 2017 Jan 19
View PubMed
Del-Carpio Munoz F
, Yao X, Abraham NS, Bellolio MF, Rabinstein AA, Asirvatham SJ, McBane RD, Gersh BJ, Shah ND, Noseworthy PA. Dabigatran Versus Warfarin in Relation to Renal Function in Patients With Atrial Fibrillation. J Am Coll Cardiol 2016 Jul 5; 68 (1):129-31
View PubMed
Rajpurohit N, Gulati R, Lennon RJ, Singh M, Rihal CS, Santrach PJ, Donato LJ, Karon BS,
Del-Carpio F
, Tak T, Motiei A, Lopes RD, Gharacholou SM. Relation of Activated Clotting Times During Percutaneous Coronary Intervention to Outcomes. Am J Cardiol. 2016 Mar 01; 117(5):703-8. Epub 2015 Dec 13.
View PubMed
Del-Carpio Munoz F
, Gharacholou SM, Munger TM, Friedman PA, Asirvatham SJ, Packer DL, Noseworthy PA. Meta-Analysis of Renal Function on the Safety and Efficacy of Novel Oral Anticoagulants for Atrial Fibrillation. Am J Cardiol. 2016 Jan 1; 117: (1)69-75.
View PubMed
Del Carpio Munoz F
, Morales GX. What’s new in resynchronization therapy in heart failure? Revista de la Federacion Argentina de Cardiologia. 2015; 44: (4)193-9.
Ebrille E, Chandra VM, Syed F,
Del Carpio Munoz F
, Nanda S, Hai JJ, Cha YM, Friedman PA, Hammill SC, Munger TM, Venkatachalam KL, Packer DL, Asirvatham SJ. Distinguishing ventricular arrhythmia originating from the right coronary cusp, peripulmonic valve area, and the right ventricular outflow tract: utility of lead I. J Cardiovasc Electrophysiol. 2014 Apr; 25 (4):404-410 Epub 2014 Jan 08
View PubMed
Lee YH, Wu JH, Asirvatham SJ,
Del Carpio Munoz F
, Webster T, Brooke KL, Hodge DO, Wiste HJ, Friedman PA, Cha YM. Effects of atrioventricular conduction delay on the outcome of cardiac resynchronization therapy. J Electrocardiol. 2014 Nov-Dec; 47(6):930-5. Epub 2014 Aug 02.
View PubMed
Vaidya V, Syed F, Desimone C, Bdeir S,
Munoz C
, Packer DL, Asirvatham SJ. Outflow tract ventricular tachycardia mapped to the coronary arteries: anatomical correlates and management strategies. J Cardiovasc Electrophysiol. 2013 Dec; 24 (12):1416-22 Epub 2013 Sept 17
View PubMed
Del-Carpio Munoz F
, Powell BD, Cha YM, Wiste HJ, Redfield MM, Friedman PA, Asirvatham SJ. Delayed intrinsicoid deflection onset in surface ECG lateral leads predicts left ventricular reverse remodeling after cardiac resynchronization therapy. Heart Rhythm. 2013 Jul; 10(7):979-87. Epub 2013 Mar 28.
View PubMed
Del Carpio Munoz F
, Powell BD, Cha YM, Wiste HJ, Redfield M, Friedman PA, Asirvatham SJ. Delayed intrinsicoid deflection in lateral ECG leads predict reverse remodeling response after cardiac resynchronization therapy. Heart Rhythm Journal Submitted. 2012.
Del Carpio Munoz F
, Buescher TL, Asirvatham SJ. Teaching points with 3-dimensional mapping of cardiac arrhythmia: how to overcome potential pitfalls during substrate mapping? Circ Arrhythm Electrophysiol. 2011 Dec; 4(6):e72-5.
View PubMed
Del-Carpio Munoz F
, Friedman PA. Catheter ablation of post myocardial infarction scar related ventricular tachycardia: role of entrainment. Indian Heart J. 2011 Jul-Aug; 63(4):371-8.
View PubMed
Del Carpio Munoz F
, Syed FF, Noheria A, Cha YM, Friedman PA, Hammill SC, Munger TM, Venkatachalam KL, Shen WK, Packer DL, Asirvatham SJ. Characteristics of premature ventricular complexes as correlates of reduced left ventricular systolic function: study of the burden, duration, coupling interval, morphology and site of origin of PVCs. J Cardiovasc Electrophysiol. 2011 Jul; 22 (7):791-8 Epub 2011 Feb 18
View PubMed
Del Carpio Munoz F
, Buescher T, Asirvatham SJ. Teaching points with 3-dimensional mapping of cardiac arrhythmias: taking points: activation mapping. Circ Arrhythm Electrophysiol. 2011 Jun; 4(3):e22-5.
View PubMed
Meas S,
Del-Carpio Munoz F
, Cetta F, Friedman P. Transseptal access for pulmonary vein isolation in a patient with atrial septal closure device: use of electrocautery and atrial septostomy. Heart Rhythm. 2011 Jun; 8: (6)901-4.
View PubMed
Del Carpio Munoz F
, Buescher TL, Asirvatham SJ. Teaching points with 3-dimensional mapping of cardiac arrhythmias: teaching point 3: when early is not early. Circ Arrhythm Electrophysiol. 2011 Apr; 4(2):e11-4.
View PubMed
Del Carpio Munoz F
, Buescher TL, Asirvatham SJ. Teaching points with 3-dimensional mapping of cardiac arrhythmia: mechanism of arrhythmia and accounting for the cycle length. Circ Arrhythm Electrophysiol. 2011 Feb; 4(1):e1-3.
View PubMed
Del Carpio Munoz F
, Buescher TL, Asirvatham SJ. Three-dimensional mapping of cardiac arrhythmias: what do the colors really mean? Circ Arrhythm Electrophysiol. 2010 Dec; 3(6):e6-11.
View PubMed
Castellanos A,
Munoz C
, Martel JA. Left-sided intraventricular conduction delay concealed by right bundle branch block. J Electrocardiol. 2008 Jul-Aug; 41 (4):357-9 Epub 2008 Mar 14
View PubMed
Castellanos A, Brenes JC, Chirinos-Medina JA,
del Carpio F
. Interpolated premature ventricular contractions with postponed compensatory pauses: a misnomer? J Electrocardiol. 2006 Oct; 39(4):377-9. Epub 2006 Mar 09.
View PubMed
Garcia S, Chirinos J, Jimenez J,
Del Carpio Munoz F
, Canoniero M, Jy W, Jimenez J, Horstman L, Ahn Y. Phenotypic assessment of endothelial microparticles in patients with heart failure and after heart transplantation: switch from cell activation to apoptosis. J Heart Lung Transplant. 2005 Dec; 24 (12):2184-9 Epub 2005 Nov 02
View PubMed
Chirinos JA, Tamariz LJ, Lopes G,
Del Carpio F
, Zhang X, Milikowski C, Lichtstein DM. Large vessel involvement in ANCA-associated vasculitides: report of a case and review of the literature. Clin Rheumatol. 2004 Apr; 23(2):152-9. Epub 2004 Jan 13.
View PubMed
.
Mayo Clinic Footer