Nikola A. Baumann, Ph.D.
Gile JJ, Maurer M, Ruan GJ, Abeykoon JP, Heimgartner JR,
Baumann NA
, McMahon M, Lin Y, Witzig TE. Low magnesium levels and prognosis in newly diagnosed diffuse large B-cell lymphoma. Oncologist. 2024 Oct 8 Epub 2024 Oct 08
View PubMed
Galior KD, Ladwig PM, Snyder MR, Algeciras-Schimnich A, Bornhorst JA, Block DR,
Baumann NA
, Willrich MAV. Lack of observed interference by therapeutic monoclonal antibodies in select commonly utilized immunoassays. Clin Biochem. 2023 Nov; 121-122:110685 Epub 2023 Nov 14
View PubMed
Fatica EM, Jenkins SM, Scott RJ, Block DR, Meeusen JW,
Baumann NA
, Saenger AK, Donato LJ. Short- and Long-Term Biological Variability of Small Dense LDL, HDL3, and Triglyceride-Rich Lipoprotein Cholesterol. J Appl Lab Med. 2022 Sep 1; 7 (5):1047-1061
View PubMed
Larkey NE, Ewaisha R, Lasho MA, Roforth MM, Granger D, Jerde CR, Wu L, Gorsh A, Klassen SA, Senefeld JW, Joyner MJ,
Baumann NA
, Theel ES, Mills JR. Limited Correlation between SARS-CoV-2 Serologic Assays for Identification of High-Titer COVID-19 Convalescent Plasma Using FDA Thresholds. Microbiol Spectr. 2022 Aug 31; 10 (4):e0115422 Epub 2022 July 05
View PubMed
Ramos P, Jenkins SM, Donato LJ, Hartman SJ, Saenger A,
Baumann NA
, Block DR, Jaffe AS, Meeusen JW. The Biological Variability of Plasma Ceramides in Healthy Subjects. J Appl Lab Med. 2022 Jun 30; 7(4):863-870.
View PubMed
Baumann NA
. Ask the expert: focus on fibrotest. Clinical Laboratory News. 2022; 48(6):48. Epub 2022 Jul 01.
Katzman B,
Baumann NA
. Investigating immunoassay interferences: polish your troubleshooting tools and avoid the red herring. Clinical Laboratory News. 2022; 48(3):4-5.
Kratzsch J,
Baumann NA
, Ceriotti F, Lu ZX, Schott M, van Herwaarden AE, Henriques Vieira JG, Lehmann H, Kasapic D, Giovanella L. The new Roche Elecsys TSH assay conforms with current IFCC C-STFT standards. Clin Chem Lab Med 2021 Nov 25; 59 (12):e445-e448 Epub 2021 July 13
View PubMed
Donato LJ, Wockenfus AM, Katzman BM,
Baumann NA
, Jaffe AS, Karon BS. Analytical and Clinical Considerations in Implementing the Roche Elecsys Troponin T Gen 5 STAT Assay. Am J Clin Pathol. 2021 Nov 8; 156 (6):1121-1129
View PubMed
Nandakumar V, Dolan CT,
Baumann NA
, Block DR. Effect of pH on the Quantification of Common Chemistry Analytes in Body Fluid Specimens Using the Roche cobas Analyzer for Clinical Diagnostic Testing. Am J Clin Pathol. 2021 Oct 13; 156 (5):722-727
View PubMed
Donato LJ, Theel ES,
Baumann NA
, Bridgeman AR, Blommel JH, Wu Y, Karon BS. Evaluation of the genalyte maverick SARS-CoV-2 multi-antigen serology panel. J Clin Virol Plus. 2021 Sep; 1 (3):100030 Epub 2021 June 19
View PubMed
Theel ES, Johnson PW, Kunze KL, Wu L, Gorsh AP, Granger D, Roforth MM, Jerde CR, Lasho M, Andersen KJ, Murphy BM, Harring J, Lake DF, Svarovsky SA, Senefeld JW, Carter RE, Joyner MJ,
Baumann NA
, Mills JR. SARS-CoV-2 Serologic Assays Dependent on Dual-Antigen Binding Demonstrate Diverging Kinetics Relative to Other Antibody Detection Methods. J Clin Microbiol. 2021 Aug 18; 59(9):e0123121.
View PubMed
Katzman BM, Hain EA, Donato LJ,
Baumann NA
. Validation of a Commercial Reagent for the Depletion of Biotin from Serum/Plasma: A Rapid and Simple Tool to Detect Biotin Interference with Immunoassay Testing. J Appl Lab Med. 2021 Jul 7; 6 (4):992-997
View PubMed
Kratzsch J,
Baumann NA
, Ceriotti F, Lu ZX, Schott M, van Herwaarden AE, Henriques Vieira JG, Kasapic D, Giovanella L. Global FT4 immunoassay standardization: an expert opinion review. Clin Chem Lab Med. 2021 May 26; 59 (6):1013-1023 Epub 2020 Dec 24
View PubMed
Gile JJ, Lopez CL, Ruan GJ, Hathcock MA, Abeykoon JP, Heimgartner JR,
Baumann NA
, McMahon MM, Micallef IN, Johnston PB, Bisneto JCV, Porrata LF, Paludo J, Ansell SM, Hogan WJ, Witzig TE. Hypomagnesemia at the time of autologous stem cell transplantation for patients with diffuse large B-cell lymphoma is associated with an increased risk of failure. Blood Cancer J. 2021 Mar 26; 11 (3):65
View PubMed
Rice ML, Go JR, Rivera CG, Zeuli JD, Saleh OA,
Baumann NA
, Stevens RW. Unexpected Vancomycin Pharmacokinetic Profile Secondary to Macromolecular Complexing: A Case Series. Ther Drug Monit. 2021 Mar 15 [Epub ahead of print]
View PubMed
Snozek CLH, Spears GM, Porco AB, Erb S, Kaleta EJ, Bryant SC,
Baumann NA
. Updated ferritin reference intervals for the Roche Elecsys(R) immunoassay. Clin Biochem. 2021 Jan; 87:100-103 Epub 2020 Nov 12
View PubMed
Galior KD,
Baumann NA
. Challenges with At-home and Mail-in Direct-to-Consumer Testing: Preanalytical Error, Reporting Results, and Result Interpretation. Clin Lab Med. 2020 Mar; 40 (1):25-36
View PubMed
Katrangi W,
Baumann NA
, Nett RC, Karon BS, Block DR. Prevalence of Clinically Significant Differences in Sodium Measurements Due to Abnormal Protein Concentrations Using an Indirect Ion-Selective Electrode Method. J Appl Lab Med. 2019 Nov; 4 (3):427-432 Epub 2019 Aug 23
View PubMed
Jara-Aguirre JC,
Baumann NA
, Block DR, Algeciras-Schimnich A. Human chorionic gonadotropin suspected heterophile interference investigations in immunoassays: a recommended approach. Clin Chem Lab Med. 2019 Jul 26; 57 (8):1192-1196
View PubMed
Klee GG, Ichihara K, Ozarda Y,
Baumann NA
, Straseski J, Bryant SC, Wood-Wentz CM. Reference Intervals: Comparison of Calculation Methods and Evaluation of Procedures for Merging Reference Measurements From Two US Medical Centers. Am J Clin Pathol. 2018 Oct 24; 150(6):545-554.
View PubMed
Katzman BM, Lueke AJ, Donato LJ, Jaffe AS,
Baumann NA
. Prevalence of biotin supplement usage in outpatients and plasma biotin concentrations in patients presenting to the emergency department. Clin Biochem. 2018 Sep; 60:11-16 Epub 2018 July 21
View PubMed
Block DR, Ouverson LJ, Wittwer CA, Saenger AK,
Baumann NA
. An approach to analytical validation and testing of body fluid assays for the automated clinical laboratory. Clin Biochem. 2018 Aug; 58:44-52 Epub 2018 May 05
View PubMed
Rosenbaum MW, Flood JG, Melanson SEF,
Baumann NA
, Marzinke MA, Rai AJ, Hayden J, Wu AHB, Ladror M, Lifshitz MS, Scott MG, Peck-Palmer OM, Bowen R, Babic N, Sobhani K, Giacherio D, Bocsi GT, Herman DS, Wang P, Toffaletti J, Handel E, Kelly KA, Albeiroti S, Wang S, Zimmer M, Driver B, Yi X, Wilburn C, Lewandrowski KB. Quality Control Practices for Chemistry and Immunochemistry in a Cohort of 21 Large Academic Medical Centers. Am J Clin Pathol. 2018 Jul 3; 150 (2):96-104
View PubMed
Parvin CA,
Baumann NA
. Assessing Quality Control Strategies for HbA1c Measurements From a Patient Risk Perspective. J Diabetes Sci Technol. 2018 Jul; 12 (4):786-791 Epub 2018 Feb 16
View PubMed
Friedman PA, Scott CG, Bailey K,
Baumann NA
, Albert D, Attia ZI, Ladewig DJ, Yasin O, Dillon JJ, Singh B. Errors of Classification With Potassium Blood Testing: The Variability and Repeatability of Critical Clinical Tests. Mayo Clin Proc. 2018 May; 93 (5):566-572
View PubMed
Karon BS, Tolan NV, Wockenfus AM, Block DR,
Baumann NA
, Bryant SC, Clements CM. Evaluation of lactate, white blood cell count, neutrophil count, procalcitonin and immature granulocyte count as biomarkers for sepsis in emergency department patients. Clin Biochem. 2017 Nov; 50 (16-17):956-958 Epub 2017 May 25
View PubMed
Donato LJ, Meeusen JW, Jenkins SM, Hartman SJ, Saenger AK,
Baumann NA
, Block DR, Jaffe AS. Biological variability of lipoprotein-associated phospholipase A2 activity in healthy individuals. Clin Biochem. 2017 Apr; 50 (6):347-349 Epub 2016 Nov 25
View PubMed
Morbeck DE,
Baumann NA
, Oglesbee D. Composition of single-step media used for human embryo culture. Fertil Steril. 2017 Apr; 107 (4):1055-1060.e1 Epub 2017 Feb 24
View PubMed
Sharma A,
Baumann NA
, Shah P. Biotin-Induced Biochemical Graves Disease: A Teachable Moment. JAMA Intern Med. 2017 Apr 1; 177 (4):571-572
View PubMed
Baumann NA
. The Importance of Effective Communication: Some Food for Thought. J Appl Lab Med. 2017 Jan 1; 1 (4):460-461
View PubMed
Tolan NV, Kaleta EJ, Fang JL, Colby CE, Carey WA, Karon BS,
Baumann NA
. Neonatal Intensive Care Unit Quality Initiative: Identifying Preanalytical Variables Contributing to Specimen Hemolysis and Measuring the Impact of Evidence-Based Practice Interventions. Am J Clin Pathol. 2016 Jul; 146 (1):113-8 Epub 2016 June 29
View PubMed
Moyer AM, Saenger AK, Willrich M, Donato LJ,
Baumann NA
, Block DR, Botz CM, Khan MA, Jaffe AS, Hanson CA, Karon BS. Implementation of Clinical Decision Support Rules to Reduce Repeat Measurement of Serum Ionized Calcium, Serum Magnesium, and N-Terminal Pro-B-Type Natriuretic Peptide in Intensive Care Unit Inpatients. Clin Chem. 2016 Jun; 62 (6):824-30 Epub 2016 Mar 28
View PubMed
Bauer PR, Kashyap R, League SC, Park JG, Block DR,
Baumann NA
, Algeciras-Schimnich A, Jenkins SM, Smith CY, Gajic O, Abraham RS. Diagnostic accuracy and clinical relevance of an inflammatory biomarker panel for sepsis in adult critically ill patients. Diagn Microbiol Infect Dis. 2016 Feb; 84 (2):175-80 Epub 2015 Oct 09
View PubMed
Meeusen JW, Rule AD, Voskoboev N,
Baumann NA
, Lieske JC. Performance of cystatin C-and creatinine-based estimated glomerular filtration rate equations depends on patient characteristics Acta Bioquimica Clinica Latinoamericana. 2016; 50: (1)107-16.
Mills JR, Greene DN, Bainton J, Lorey TS,
Baumann NA
. Fluctuating serum aspartate aminotransferase activity in a complicated pregnancy. Clin Chem. 2015 Oct; 61 (10):1241-4
View PubMed
Meeusen JW, Rule AD, Voskoboev N,
Baumann NA
, Lieske JC. Performance of cystatin C- and creatinine-based estimated glomerular filtration rate equations depends on patient characteristics. Clin Chem. 2015 Oct; 61 (10):1265-72 Epub 2015 Aug 03
View PubMed
Meeusen JW, Snozek CL,
Baumann NA
, Jaffe AS, Saenger AK. Reliability of Calculated Low-Density Lipoprotein Cholesterol. Am J Cardiol. 2015 Aug 15; 116(4):538-40. Epub 2015 May 21.
View PubMed
Willrich MA, Wittwer CA,
Baumann NA
, Block DR. A dark-brown serum sample. Clin Chem. 2015 Jul; 61(7):999-1000.
View PubMed
Abu Dayyeh BK, Conwell D, Buttar NS, Kadilaya V, Hart PA,
Baumann NA
, Bick BL, Chari ST, Chowdhary S, Clain JE, Gleeson FC, Lee LS, Levy MJ, Pearson RK, Petersen BT, Rajan E, Steen H, Suleiman S, Banks PA, Vege SS, Topazian M. Pancreatic juice prostaglandin e2 concentrations are elevated in chronic pancreatitis and improve detection of early disease. Clin Transl Gastroenterol. 2015 Jan 29; 6:e72
View PubMed
Morbeck DE, Paczkowski M, Fredrickson JR, Krisher RL, Hoff HS,
Baumann NA
, Moyer T, Matern D. Composition of protein supplements used for human embryo culture. J Assist Reprod Genet. 2014 Dec; 31 (12):1703-11 Epub 2014 Sept 27
View PubMed
Donin NM, Loeb S, Cooper PR, Roehl KA,
Baumann NA
, Catalona WJ, Helfand BT. Genetically adjusted prostate-specific antigen values may prevent delayed biopsies in African-American men. BJU Int. 2014 Dec; 114 (6b):E50-E55 Epub 2014 July 15
View PubMed
Akbas N, Schryver PG, Algeciras-Schimnich A,
Baumann NA
, Block DR, Budd JR, Gaston SJ, Klee GG. Evaluation of Beckman Coulter DxI 800 immunoassay system using clinically oriented performance goals. Clin Biochem. 2014 Nov; 47(16-17):158-63. Epub 2014 Aug 15.
View PubMed
Morbeck DE, Krisher RL, Herrick JR,
Baumann NA
, Matern D, Moyer T. Composition of commercial media used for human embryo culture. Fertil Steril. 2014 Sep; 102(3):759-766.e9. Epub 2014 Jul 04.
View PubMed
Tange JI, Grill D, Koch CD, Ybabez RJ, Krekelberg BJ, Fylling KA, Wiese CR,
Baumann NA
, Block DR, Karon BS, Chen D, Pruthi RK. Local verification and assignment of mean normal prothrombin time and International Sensitivity Index values across various instruments: recent experience and outcome from North America. Semin Thromb Hemost. 2014 Feb; 40(1):115-20. Epub 2013 Dec 31.
View PubMed
Helfand BT, Loeb S, Hu Q, Cooper PR, Roehl KA, McGuire BB,
Baumann NA
, Catalona WJ. Personalized prostate specific antigen testing using genetic variants may reduce unnecessary prostate biopsies. J Urol. 2013 May; 189(5):1697-701. Epub 2013 Feb 27.
View PubMed
Ichihara K, Ozarda Y, Klee G, Straseski J,
Baumann N
, Ishikura K, Committee on Reference Intervals and Decision Limits International Federation for Clinical Chemistry and Laboratory Medicine. Utility of a panel of sera for the alignment of test results in the worldwide multicenter study on reference values. Clin Chem Lab Med. 2013 May; 51(5):1007-25.
View PubMed
Kaleta EJ, Jaffe AS,
Baumann NA
, Block DR. A case of floating gel. Clin Chem. 2012 Nov; 58 (11):1604-5
View PubMed
Murata K,
Baumann NA
, Saenger AK, Larson TS, Rule AD, Lieske JC. Relative performance of the MDRD and CKD-EPI equations for estimating glomerular filtration rate among patients with varied clinical presentations. Clin J Am Soc Nephrol. 2011 Aug; 6 (8):1963-72 Epub 2011 July 07
View PubMed
Le BV, Griffin CR, Loeb S, Carvalhal GF, Kan D,
Baumann NA
, Catalona WJ. [-2]Proenzyme prostate specific antigen is more accurate than total and free prostate specific antigen in differentiating prostate cancer from benign disease in a prospective prostate cancer screening study. J Urol. 2010 Apr; 183(4):1355-9. Epub 2010 Feb 19.
View PubMed
McGee KM,
Baumann NA
. Procalcitonin. Clinical Laboratory News. 2009 Jul; 35(7).
Gelsthorpe ME,
Baumann N
, Millard E, Gale SE, Langmade SJ, Schaffer JE, Ory DS. Niemann-Pick type C1 I1061T mutant encodes a functional protein that is selected for endoplasmic reticulum-associated degradation due to protein misfolding. J Biol Chem. 2008 Mar 28; 283(13):8229-36. Epub 2008 Jan 23.
View PubMed
Barak V, Frenkel S, Valyi-Nagy K, Leach L, Apushkin MA, Lin AY, Kalickman I,
Baumann NA
, Pe'er J, Maniotis AJ, Folberg R. Using the direct-injection model of early uveal melanoma hepatic metastasis to identify TPS as a potentially useful serum biomarker. Invest Ophthalmol Vis Sci. 2007 Oct; 48(10):4399-402.
View PubMed
Baumann NA
, Gronowski AM. Establishment of reference intervals for thyroid- stimulating hormone and free thyroxine in amniotic fluid using the Bayer ADVIA Centaur. Am J Clin Pathol. 2007 Jul; 128(1):158-63.
View PubMed
Sullivan DP, Ohvo-Rekila H,
Baumann NA
, Beh CT, Menon AK. Sterol trafficking between the endoplasmic reticulum and plasma membrane in yeast. Biochem Soc Trans. 2006 Jun; 34(Pt 3):356-8.
View PubMed
Baumann NA
, Sullivan DP, Ohvo-Rekila H, Simonot C, Pottekat A, Klaassen Z, Beh CT, Menon AK. Transport of newly synthesized sterol to the sterol-enriched plasma membrane occurs via nonvesicular equilibration. Biochemistry. 2005 Apr 19; 44(15):5816-26.
View PubMed
Baumann NA
, Vidugiriene J, Machamer CE, Menon AK. Cell surface display and intracellular trafficking of free glycosylphosphatidylinositols in mammalian cells. J Biol Chem. 2000 Mar 10; 275(10):7378-89.
View PubMed
Vidugiriene J, Sharma DK, Smith TK,
Baumann NA
, Menon AK. Segregation of glycosylphosphatidylinositol biosynthetic reactions in a subcompartment of the endoplasmic reticulum. J Biol Chem. 1999 May 21; 274(21):15203-12.
View PubMed
Menon AK,
Baumann NA
, van't Hof W, Vidugiriene J. Glycosylphosphatidylinositols: biosynthesis and intracellular transport. Biochem Soc Trans. 1997 Aug; 25(3):861-5.
View PubMed
.
Mayo Clinic Footer