Print OverviewCholine C-11 PET scan is an imaging test used to help detect sites of prostate cancer that has returned despite treatment (recurrent prostate cancer). It may be used when other imaging hasn't been helpful. Choline C-11 PET scan is a positron emission tomography (PET) scan that uses a special chemical tracer called Choline C-11 Injection. A low-dose computerized tomography (CT) scan is usually done at the same time to help further show internal anatomy. Choline C-11 PET scan may help doctors detect possible sites of recurrent prostate cancer that more-conventional imaging tests can't identify. Locating recurrent prostate cancer sooner may allow your doctor to identify small, isolated deposits of cancer — within the prostate and outside of the prostate — that can be targeted for more-effective treatment. Choline C-11 PET scan uses a radioactive form of the vitamin choline. A small amount of the tracer is injected into a vein in your arm just before the scan is done. Prostate cancer cells in your body readily absorb the tracer. This can help doctors detect areas of prostate cancer cells throughout your body. A biopsy to remove some cells for lab testing is then done to confirm the presence of recurrent prostate cancer.Products & ServicesA Book: Man Overboard!A Book: Mayo Clinic on Prostate HealthShow more products from Mayo Clinic By Mayo Clinic Staff Choline C-11 PET scan care at Mayo Clinic Request an appointment Doctors & Departments Nov. 03, 2022 Print Show references Choline C-11 Injection (prescribing information). Rochester, Minn.: Mayo Clinic PET Radiochemistry Facility; 2012. https://www.accessdata.fda.gov/scripts/cder/daf/index.cfm?event=overview.process&ApplNo=203155. Accessed Dec. 3, 2018. Prostate cancer. Plymouth Meeting, Pa.: National Comprehensive Cancer Network. https://www.nccn.org/professionals/physician_gls/f_guidelines.asp. Accessed Dec. 3, 2018. Evans JD, et al. Prostate cancer-specific PET radiotracers: A review on the clinical utility in recurrent disease. Practical Radiation Oncology. 2018;8:28. Murphy RC, et al. The utility of 11C-choline PET/CT for imaging prostate cancer: A pictorial guide. American Journal of Roentgenology. 2011;196:1390. Related Prostate cancer Products & Services A Book: Man Overboard! A Book: Mayo Clinic on Prostate Health Show more products and services from Mayo Clinic Mayo Clinic in Rochester, Minnesota, has been recognized as one of the top Urology hospital in the nation for 2024-2025 by U.S. News & World Report. Learn more about this top honor Choline C-11 PET scanAboutDoctors&DepartmentsCare atMayoClinic Advertisement Mayo Clinic does not endorse companies or products. Advertising revenue supports our not-for-profit mission. Advertising & Sponsorship Policy Opportunities Ad Choices Mayo Clinic Press Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. NEW: Listen to Health Matters Podcast - Mayo Clinic PressNEW: Listen to Health Matters PodcastMayo Clinic on Incontinence - Mayo Clinic PressMayo Clinic on IncontinenceThe Essential Diabetes Book - Mayo Clinic PressThe Essential Diabetes BookMayo Clinic on Hearing and Balance - Mayo Clinic PressMayo Clinic on Hearing and BalanceFREE Mayo Clinic Diet Assessment - Mayo Clinic PressFREE Mayo Clinic Diet AssessmentMayo Clinic Health Letter - FREE book - Mayo Clinic PressMayo Clinic Health Letter - FREE book PRC-20155328 Patient Care & Health Information Tests & Procedures Choline C-11 PET scan